Influenza is vaccine-preventable; however, the burden of severe influenza in India remains unknown. We conducted a population-based study to estimate the incidence of laboratory confirmed influenza-associated hospitalizations in a rural community in western India.

A 25-year, US$10-billion global effort has taken the number of polio cases from hundreds of thousands per year to just hundreds, but it is now struggling to stamp the virus out of its final strongholds in Pakistan, Afghanistan and Nigeria, where transmission has never been interrupted. Of these, Nigeria was the only one to see an increase in cases from 2011 to 2012, and public-health experts worry that the virus's recalcitrance here will prevent global eradication, and eventually lead to a wider resurgence of the disease.

Kyasanur forest disease (KFD), a tick-borne viral disease with hemorrhagic manifestations, is localised in five districts of Karnataka state, India. Annual rounds of vaccination using formalin inactivated tissue-culture vaccine have been conducted in the region since 1990. Two doses of vaccine are administered to individuals aged 7–65 years at an interval of one month followed by periodic boosters after 6–9 months. In spite of high effectiveness of the vaccine reported in earlier studies, KFD cases among vaccinated individuals have been recently reported.

Viral hepatitis constitutes an enormous health burden, and is a major cause of morbidity and mortality globally. The magnitude of the problem can be highlighted by the fact that 1 in 12 people globally are living with chronic infections of either hepatitis B

An engineered influenza virus based on a haemagglutinin protein from H5N1 avian influenza, with just four mutations, can be transmitted between ferrets, emphasizing the potential for a human pandemic to emerge from birds.