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Postural changes in blood pressure associated with interactions between candidate genes for chronic respiratory diseases

Fine particulate matter [aerodynamic diameter ? 2.5 ?m (PM2.5)] has been associated with autonomic dysregulation. The authors hypothesized that PM2.5 influences postural changes in systolic blood pressure (?SBP) and in diastolic blood pressure (?DBP) and that this effect is modified by genes thought to be related to chronic lung disease.