The recent trends of increasing awareness of economic and environmental cost of conventional landfilling are being developed in accelerating pace for the degradation of the organic fraction of municipal solid waste (MSW). The anaerobic digestion (AD) is viewed as an attractive method for waste stabilization prior to landfills as a pre-treatment processing to reduce the significant fraction of organic pollutant as well as to generate methane as a fuel gas. Batch studies were carried out in aspirator bottles of different capacities to select critical factors influencing the single stage high solid (SSHS) approach development with an emphasis on C/N ratio.