TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles

  • 31/05/2011

  • Environmental Health Perspectives

Human respiratory epithelia function in airway mucociliary clearance and barrier function and have recently been implicated in sensory functions. The authors investigated a link between chronic obstructive pulmonary disease (COPD) pathogenesis and molecular mechanisms underlying Ca2+ influx into human airway epithelia elicited by diesel exhaust particles (DEP).