Ebola Virus Disease (Ebola Hemorrhagic Fever)

Order of the National Green Tribunal regarding pollution of Godavari river, Telangana, 29/05/2025

Order of the National Green Tribunal in the matter of News Item titled "Telangana: Deepening pollution crisis in Godawari threatens lives livelihoods appearing in the Telangana Today dated 13.05.2025" dated 29/05/2025. The application was registered suo-motu on the basis of the news item titled Telangana: Deepening pollution crisis in Godawari …

Ebola experimental vaccine is highly effective, trial shows

Trials conducted in Guinea, one of the West African countries most affected by an outbreak of Ebola that ended this year, show it offers 100% protection. The vaccine is now being fast-tracked through regulatory approval. Manufacturer Merck says it will make 300,000 doses of the rVSV-ZEBOV vaccine available for future …

Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

rVSV-ZEBOV is a recombinant, replication competent vesicular stomatitis virus-based candidate vaccine expressing a surface glycoprotein of Zaire Ebolavirus. We tested the effect of rVSV-ZEBOV in preventing Ebola virus disease in contacts and contacts of contacts of recently confirmed cases in Guinea, west Africa. Original Source

Identifying future disease hot spots: infectious disease vulnerability index

The report presents the Infectious Disease Vulnerability Index as a method for identifying the most vulnerable countries to such outbreaks so that they might be higher priorities for technical and funding support. The index was designed to help inform decision making for the mitigation of potential outbreaks. Key findings from …

The evolution of Ebola virus: Insights from the 2013–2016 epidemic

The 2013–2016 epidemic of Ebola virus disease in West Africa was of unprecedented magnitude and changed our perspective on this lethal but sporadically emerging virus. This outbreak also marked the beginning of large-scale realtime molecular epidemiology. Here, we show how evolutionary analyses of Ebola virus genome sequences provided key insights …

‘India a key player in developing vaccines’

Attesting India’s expanding role in fighting epidemics, Peter Piot, the co-discoverer of Ebola virus, said India is a key player in the global initiative to develop vaccines. Speaking to The Hindu during an interaction with researchers at the India Institute of Public Health in Hyderabad, Prof. Piot said India along …

Safe workers save lives

A study of the World Bank Group indicated that “as of May 2015, 0.11% of Liberia’s entire general population had died due to Ebola, as compared with 8.07% of its health workers, defined in the study as doctors, nurses and midwives. In Sierra Leone, the loss was 0.06% of the …

A unified framework for the infection dynamics of zoonotic spillover and spread

A considerable amount of disease is transmitted from animals to humans and many of these zoonoses are neglected tropical diseases. As outbreaks of SARS, avian influenza and Ebola have demonstrated, however, zoonotic diseases are serious threats to global public health and are not just problems confined to remote regions. There …

Monkeys protect against lethal Ebola Sudan infection four days after infection

Researchers at The University of Texas Medical Branch at Galveston, in collaboration with Arbutus Biopharma Corporation, have protected nonhuman primates against Ebola Sudan four days following exposure to the virus. The study results, which were recently published in Nature Microbiology, demonstrated that the treatment was effective at a point when …

Updates to the zoonotic niche map of Ebola virus disease in Africa

As the outbreak of Ebola virus disease (EVD) in West Africa is now contained, attention is turning from control to future outbreak prediction and prevention. Building on a previously published zoonotic niche map (Pigott et al., 2014), this study incorporates new human and animal occurrence data and expands upon the …

Undiscovered bat hosts of Filoviruses

Ebola and other filoviruses pose significant public health and conservation threats by causing high mortality in primates, including humans. Preventing future outbreaks of ebolavirus depends on identifying wildlife reservoirs, but extraordinarily high biodiversity of potential hosts in temporally dynamic environments of equatorial Africa contributes to sporadic, unpredictable outbreaks that have …

Progress towards protection from highly lethal Ebola, Marburg viruses

Ebola and Marburg filovirus disease outbreaks have typically occurred as isolated events, confined to central Africa. However, the recent Ebola epidemic spread to several African countries, and caused 11,000 deaths. That epidemic underscored the need to develop vaccines and therapeutics that could be used to fight future disease outbreaks. Now …

MIT’s Customizable RNA Vaccine Allows For Rapid Deployment to Ebola-Stricken Areas

Engineers at the Massachusetts Institute of Technology (MIT) have developed a new type of customizable vaccine that could work against Ebola and other disease outbreaks, and could be deployed faster than traditional vaccines. The vaccine can be manufactured in one week, which allows for rapid deployment to areas affected by …

Human survivors of disease outbreaks caused by Ebola or Marburg viruses exhibit cross-reactive and long-lived antibody responses

A detailed understanding of serological immune responses to Ebola and Marburg virus infections will facilitate the development of effective diagnostic methods, therapeutics and vaccines. We examined antibodies from Ebola or Marburg survivors 1-14 years after recovery from disease, by using a microarray that displayed recombinant nucleoprotein (NP), viral protein 40 …

Global patterns of zoonotic disease in mammals

As the frequency and prevalence of zoonotic diseases increase worldwide, investigating how mammal host distributions determine patterns of human disease and predicting which regions are at greatest risk for future zoonotic disease emergence are two goals which both require better understanding of the current distributions of zoonotic hosts and pathogens. …

New model helps predict Ebola, Zika by observing environmental changes

Researchers used the locations of 408 known Lassa fever outbreaks in West Africa between 1967-2012 and the changes in land use and crop yields, temperature and rainfall, behaviour and access to healthcare. Scientists have successfully developed a model that can predict the outbreak of diseases that spread from animals to …

Chinese scientists develop portable device to detect Ebola quickly

A team of scientists from a Chinese university have developed a palm-sized instrument that can detect the Ebola virus more quickly than traditional way and track down the virus load in body fluid. In the traditional method, doctors or scientists have to use a method called reverse-transcription polymerase chain reaction …

Could deadly animal disease bluetongue become the next Ebola?

Agra: Could a deadly animal disease that arrived on our shores less than 40 years ago cross over to humans, like Ebola, bubonic plague and HIV? A five-year-long research project in the department of entomology at St John's College here is trying to determine just that. Dr Girish Maheshwari, an …

Kenyan research institute to launch Ebola vaccine trial in July

An Ebola clinical vaccine trial will be launched this July by the Kenya Medical Research Institute (KEMRI), the Standard Digital of Kenya reports. According to Senior Deputy Director of the KEMRI Walter Reed project, Dr Fredric Sawe, the effort by KEMRI is meant to restore the West African region which …

Digital payments to Ebola emergency staff saved over $10m - UN study

Digital payments to emergency workers saved time and more than $10m in costs during the Ebola epidemic in Sierra Leone, a United Nations-backed initiative has found. The study by the ‘Better Than Cash Alliance’ (BTCA), a partnership of governments, companies and international organisations, found that most of the cost savings …

IBM Develops New Approach in Dealing with Zika, Flu, Other Viral Infections

The widespread of Zika Virus is still imminent, leaving scientist scrambling off their feet in search for potential cures and vaccines. IBM decided to join the fray against the virus and introduced a new weapon that can potentially put a stop in the spread of Zika and other viral infections …

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