Order of the Supreme Court of India in the matter of Network of People Living With HIV/AIDS & Others Vs Union of India & Others dated 24/02/2025. The Supreme Court (SC), February 24, 2025 has directed all states to file their affidavits addressing concerns raised about antiretroviral therapy (ART) drugs …
The aim of this document is to assist national tuberculosis (TB) programmes in developing the strongest possible mechanisms of surveillance for drug resistance in TB, building on more than 25 years of global experience. This starts from periodic surveys of sampled patients, moving towards an ultimate goal of continuous surveillance …
CSE laboratory tests find high levels of antibiotics in well-known brands of honey sold in the market. Antibiotics are found in honey largely because they are used in apiculture for treatment of bacterial diseases. Oxytetracycline is commonly used to treat European foulbrood disease (EFB) and American foulbrood diseases (AFB) caused …
Covid-19 has strengthened the case for developing intra-African regional value chains and unlocking the continent’s business potential through the African Continental Free Trade Area (AfCFTA). Covid‑19 has magnified Africa’s reliance on imported pharmaceuticals (both final and intermediate products) and amplified the urgency to build competitive, resilient and robust value chains …
The objective of the study wast to assess the effectiveness of hydroxychloroquine in patients admitted to hospital with coronavirus disease 2019 (covid-19) pneumonia who require oxygen.
The objective of the study was to assess the efficacy and safety of hydroxychloroquine plus standard of care compared with standard of care alone in adults with coronavirus disease 2019 (covid-19).
The coronavirus disease 2019 (COVID-19) drug pipeline is not growing at quite the same speed as the pandemic. But its rate of expansion is nevertheless cause for pause. In the months since COVID-19 has spread, researchers have launched more than 180 clinical trials of everything from repurposed antivirals and immuno …
Ranitidine hydrochloride (Zantac) is one of the most extensively studied and widely used drugs of all time. This has provided an excellent opportunity to define its safety profile. Original Source
Researchers conducted a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2 infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxygen (Pao2) to the fraction of …
The Indian Council of Medical Research (ICMR) has obtained permission for “restricted use in public health emergency” of two second-line HIV medications for use against the novel coronavirus (nCoV). Top Health Ministry officials said these medications are to be used only in “vulnerable” cases, as they are not without side-effects. …
Despite Nipah virus outbreaks having high mortality rates (>70% in Southeast Asia), there are no licensed drugs against it. In this study, we have considered all 9 Nipah proteins as potential therapeutic targets and computationally identified 4 putative peptide inhibitors (against G, F and M proteins) and 146 small molecule …
Question raised in Lok Sabha on Drug Resistant TB Cases, 06/12/2019. India has the largest number of individuals suffering from drug resistant TB. However, as per the latest global TB report, India ranks 38th in the number of MDR-TB patients per lakh population (9.6 per lakh population). The estimated number …
The key objective of this research was to generate new evidence on outpatient antibiotic prescription rate and patterns in the private sector in India. We used 12-month period (May 2013 to April 2014) medical audit dataset from IQVIA (formerly IMS Health). We coded the diagnosis provided in the medical audit …
Antimicrobial resistance (AMR) is a priority for surveillance in bacterial infections. For leprosy, AMR has not been assessed because Mycobacterium leprae does not grow in vitro. We aim to obtain AMR data using molecular detection of resistance genes and to conduct a prospective open survey of resistance to antileprosy drugs …
The bi-directional relationship between poverty and tuberculosis (TB) is well established. Poverty aggravates material disadvantage, social exclusion, discrimination in participation across a wide range of socio-economic and behavioural activities along with undernutrition, overcrowding, lack of access to healthcare and other social determinants of health. Original Source
In light of established principles and strategies for appropriate use of antimicrobial medicines, this paper examines studies on antimicrobial use trends across several countries in the Asia and Pacific regions. The author draws upon the outcomes of these studies, which look at prescribing patterns and consumer perceptions regarding antimicrobials, to …
According to the World Health Organisation (WHO), Colistin is a “reserve” antibiotic, which means it is supposed to be considered a “last-resort” option in treatment and used only in the most severe circumstances, when all other alternatives have failed. The Health Ministry has ordered a ban on using antibiotic Colistin …
These rules aim to make available a database of clinical establishments which are authorised to function and thereby improve public health quality by eliminating quacks The Union Ministry of public health and family welfare on July 17 has issued the Clinical Establishments (Central Government) Third Amendment Rules 2019 and the …
Antimicrobial resistance (AMR) – in which a microorganism (such as a bacterium, virus, fungus or parasite) becomes resistant to an antimicrobial drug used to treat infections caused by it – is possibly the most serious public health threat of our time. Recognising the gravity of the problem, the international community …
MUMBAI: Pharma major Gilead Sciences has failed to deliver on promises to make an important drug available to patients suffering from a life-threatening HIV-related infection in certain developing countries including India, the medical humanitarian organisation Médecins Sans Frontières (MSF) said. Nearly one year ago, Gilead announced its ‘access initiative’ promising …
