Order of the Supreme Court regarding ART drugs for people living with HIV/AIDS, 24/02/2025

Order of the Supreme Court of India in the matter of Network of People Living With HIV/AIDS & Others Vs Union of India & Others dated 24/02/2025. The Supreme Court (SC), February 24, 2025 has directed all states to file their affidavits addressing concerns raised about antiretroviral therapy (ART) drugs …

Drugs of 18 pharma firms found substandard since 2018

The Bureau of Pharma PSUs of India (BPPI), which implements the Centre’s flagship affordable medicine scheme PMBJP, has found 25 batches of drugs of 18 pharmaceutical companies to be of substandard quality since January 2018, according to an official document. While 17 out of the 18 companies are private, one …

Intellectual Property Rights: Excluding other rights of other people

This article interrogates the claims of intellectual property to be a right. Drawing on the political theory of rights, it argues that information, ideas and knowledge fail to meet the basic test of rights and intellectual property right prevents those who do not own it from accessing and exercising their …

Curd-peptide based novel hydrogel inhibits biofilm formation, quorum sensing, swimming mortility of multi-antibiotic resistant clinical isolates and accelerates wound healing activity

The search for a bioactive natural antibacterial agent with wound healing properties is a common practice for the development of new-generation molecules. Antimicrobial peptides are a good alternative to antibiotics and easy-to-form hydrogels under self-assembled conditions without pH adjustment. With this in mind, the peptide pool was extracted from a …

Association of maternal folate intake during pregnancy with infant asthma risk

Several studies assessed the association of maternal folate intake with infant asthma risk, but the fndings are controversial. We performed a meta-analysis to clarify the association between maternal folate intake and infant asthma risk. Original Source

Development of antiseptic adaptation and cross-adapatation in selected oral pathogens in vitro

There is evidence that pathogenic bacteria can adapt to antiseptics upon repeated exposure. More alarming is the concomitant increase in antibiotic resistance that has been described for some pathogens. Unfortunately, efects of adaptation and cross-adaptation are hardly known for oral pathogens, which are very frequently exposed to antiseptics. Therefore, this …

Pune health dept floats proposal for independent TB control cell

A status check by the TB control unit of the PMC showed that out of 710 private hospitals/ nursing homes, 24 were reporting TB cases while six laboratories out of 406 were sending the information. The Pune Municipal Corporation (PMC) health department has floated a proposal to set up an …

Uganda to start Ebola vaccine trials

The trial is going to use the Janssen Ebola Vaccine that was developed by Janssen Pharmaceutical Company. Phase I and II human trials of the vaccine have already been carried out by the Oxford Vaccine Group in the United Kingdom. The study will be carried out at Mbarara University of …

Doctors and drug companies: Still cozy after all these years

David Henry discusses a research article by Geoffrey Spurling and colleagues that examined the relationship between exposure to promotional material from pharmaceutical companies and the quality, quantity, and cost of prescribing. Original Source

Conflict of interest reporting by authors involved in promotion of off-label drug use: An analysis of journal disclosures

Aaron Kesselheim and colleagues investigate conflict of interest disclosures in articles authored by physicians and scientists identified in whistleblower complaints alleging illegal off-label marketing by pharmaceutical companies. Original Source

No time to wait: securing the future from drug-resistant infections

UN, international agencies and experts released a groundbreaking report demanding immediate, coordinated and ambitious action to avert a potentially disastrous drug-resistance crisis. If no action is taken - warns the UN Ad hoc Interagency Coordinating Group on Antimicrobial Resistance who released the report - drug-resistant diseases could cause 10 million …

Malawi Piloting the World's First Malaria Vaccine

Malawi government says a vaccine against malaria could be a vital new tool in the fight against the debilitating illness as the Ministry of Health starts immunising children in the world's first large-scale pilot of RTS, S -- the candidate vaccine that is furthest along in development --from April 23 …

Measles, Mumps, Rubella Vaccination and Autism: A nationwide cohort study

The hypothesized link between the measles, mumps, rubella (MMR) vaccine and autism continues to cause concern and challenge vaccine uptake. The objective of the study was to evaluate whether the MMR vaccine increases the risk for autism in children, subgroups of children, or time periods after vaccination. Original Source

Order of the Delhi High Court regarding permission to avail “Human Embryonic Stem Cell Therapy”, 15/04/2019

Order of the Delhi High Court in the matter of Aditya Bhatia Vs Union of India & Others dated 15/04/2019 regarding permission to avail “Human Embryonic Stem Cell Therapy” being provided to the petitoner (Aditya Bhatia) by Nutech Mediworld. The petitioner states that he is suffering from Facioscapulohumeral Muscular Dystrophy …

Tuberculosis and social networks: a narrative review on how social network data and metrics help explain tuberculosis transmission

Social network data of tuberculosis (TB) patients could explain the source and pattern of disease spread. A review of the published literature highlights that social network data could identify hidden social or epidemiological links among TB patients and improved TB case finding. Index and betweenness position of patients explained TB …

Diabetes drug also helps kidney, heart

NEW DELHI: A drug used in India and abroad for over four years to control blood sugar has been found to also reduce kidney damage in diabetics by over 30% — a finding that could have huge impact on diabetes management. The drug, canagliflozin, a sodium glucose transporter 2 inhibitor, …

India short of 6 lakh doctors, 2 million nurses: U.S. study

The study also noted that lack of access to antibiotics kills more people than antibiotic resistance. Report highlights lack of access to life-saving drugs India has a shortage of an estimated 600,000 doctors and 2 million nurses, say scientists who found that the lack of staff who are properly trained …

Award-winning start-up targets affordable medicine for every African

A Ghana-based start-up has received $1.5 million from Ebay billionaire Jeff Skoll to support its work in changing Africa's pharmaceutical industry to make medicines more affordable. MPharma is one of five social businesses to receive awards from the Skoll Foundation at this week's Skoll World Forum, Britain's leading event for …

Fish slime: An untapped source of potential new antibiotics

As current antibiotics dwindle in effectiveness against multidrug-resistant pathogens, researchers are seeking potential replacements in some unlikely places. Now a team has identified bacteria with promising antibiotic activity against known pathogens—even dangerous organisms, such as the microbe that causes MRSA infections—in the protective mucus that coats young fish. The researchers …

Govt. notifies new rules for drugs, clinical trials

The Union Health Ministry has notified the Drugs and Clinical Trials Rules, 2019, with the government stating that the move is aimed at promoting clinical research in the country. The rules will apply to all new drugs, investigational new drugs for human use, clinical trials, bio-equivalence studies and ethics committees. …

ISCR: New rules for drugs, clinical trials to protect rights, safety of patients

The new Clinical Trial Rules, the ISCR said, has reduced the time for approving applications to 30 days for drugs discovered in India or whose research and development has been done in India and are proposed to be manufactured and marketed in India. For drugs developed outside the country, the …

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