Order of the Supreme Court of India in the matter of Network of People Living With HIV/AIDS & Others Vs Union of India & Others dated 24/02/2025. The Supreme Court (SC), February 24, 2025 has directed all states to file their affidavits addressing concerns raised about antiretroviral therapy (ART) drugs …
Malaria continues to be a major health problem globally. There is an urgent need to find new antimalarials. Acriflavine (ACF) is known as an antibacterial agent and more recently as an anticancer agent. Here, we report that ACF inhibits the growth of asexual stages of both chloroquine (CQ) sensitive and …
BANGKOK—Resistance to the world's most effective drug against malaria is becoming widespread in Southeast Asia, a recurrent pattern that threatens global efforts to control the mosquito-borne infectious disease, a new study shows. Resistance to the drug, artemisinin, in the most deadly form of malaria-causing parasite, Plasmodium falciparum, is established in …
Efforts to develop the first new malaria treatment in 20 years advanced as a pill from Novartis AG (NOVN) cleared parasites faster than the best medicines, potentially providing a solution to the spread of drug resistance. In a study among 21 patients in Thailand, Novartis’s KAE609 wiped out half the …
Making malaria vaccine available for routine use will be a major milestone, researchers say Experts say the world's first malaria vaccine could be approved for use in 2015. Reporting in PLOS Medicine, researchers found that for every 1,000 children who received the vaccine, an average of 800 cases of illness …
Health ministry seeks `500 cr for scheme The Narendra Modi government will roll out the first instalment of its ambitious `health assurance for all' promise by providing 50 essential drugs free by year end. As a first step, the Union health ministry has sent a proposal to the Prime Minister's …
Believed To Cure 90% Of Patients Even as a controversy rages globally over the eye-popping price of US firm Gilead Science’s hepatitis C drug at $1,000 a pill, Indian patients have already begun importing the medicine from countries like Canada, spending, in some cases, up to Rs 1 crore. The …
microRNAs (miRNAs) regulate expression by promoting degradation or repressing translation of target transcripts. miRNA target sites have been catalogued in databases based on experimental validation and computational prediction using various algorithms. Several online resources provide collections of multiple databases but need to be imported into other software, such as R, …
AIDS researchers seeking to cure HIV with a one-two punch got an early hint the approach may work by successfully using an old cancer drug to kick the virus out of hiding in a pilot study in Denmark. Researchers from Aarhus University gave the medicine romidepsin to six HIV-infected people …
Treatment guidelines for asthma recommend inhaled corticosteroids (ICS) as first-line therapy for children with persistent asthma. Although ICS treatment is generally considered safe in children, the potential systemic adverse effects related to regular use of these drugs have been and continue to be a matter of concern, especially the effects …
The number of people who are newly infected with HIV is continuing to decline in most parts of the world. There were 2.1 million [1.9 million–2.4 million] new HIV infections in 2013—a decline of 38% from 2001, when there were 3.4 million [3.3 million–3.6 million] new infections. In the past …
Antibiotic use has surged by 36% worldwide in a decade, much of it unwarranted, according to a new study. The rise, particularly in countries with a burgeoning middle class, heightens concerns that overuse of antibiotics is leaving more of the world's population vulnerable to drug-resistant bacteria, according to the authors …
Implementing patient cost sharing in the form of copayments, coinsurance, and deductibles is one of the more reliable methods for reducing health care costs. But imposing cost sharing reduces patients' demand for medical care, which sets the interests of insurers at odds with the interests of health care providers and …
Wants cos to ensure early launch of new therapies here if trials prove successful This move is part of steps DCGI has taken last week to bring clarity in the clinical trials space and ensure patients are not exploited Multinational pharmaceutical companies keen to conduct clinical trials for new drugs …
Genetic testing can help prevent breast cancer. The test is yet to gain popularity in India. Dr Devinder Singh Sandhu, oncologist and haematologist, attended a conference at the US recently. He said: “If you have a family history or have had high-risk benign breast disease in the past, talk to …
The malaria parasite Plasmodium falciparum exports several hundred proteins into the infected erythrocyte that are involved in cellular remodeling and severe virulence. The export mechanism involves the Plasmodium export element (PEXEL), which is a cleavage site for the parasite protease, Plasmepsin V (PMV). The PMV gene is refractory to deletion, …
PUNE: Improved reporting of tuberculosis (TB) cases by private doctors in the city is helping the Pune Municipal Corporation (PMC) understand the burden of disease, which will eventually help strengthen the state's healthcare system. As against 432 cases notified by private doctors in 2012, the reporting has gone up considerably …
