Order of the National Green Tribunal in the matter of In Re: News Item titled "Nayar river is vanishing - a yatra reveals conservation goes beyond science and policy" appearing in ‘The Down To Earth’ dated 03.06.2025. The original application was registered suo-motu based on the news item titled "Nayar …
Engineers at the Massachusetts Institute of Technology (MIT) have developed a new type of customizable vaccine that could work against Ebola and other disease outbreaks, and could be deployed faster than traditional vaccines. The vaccine can be manufactured in one week, which allows for rapid deployment to areas affected by …
Congenital sodium diarrhoea (CSD) refers to a form of secretory diarrhoea with intrauterine onset and high faecal losses of sodium without congenital malformations. The molecular basis for CSD remains unknown. We clinically characterised a cohort of infants with CSD and set out to identify disease-causing mutations by genome-wide genetic testing. …
South Africa has more people living with HIV, an estimated 6.6 million, than any country in the world. About half are now receiving antiretroviral (ARV) treatment, which has greatly stressed the country's health care system. Now, South Africa plans to encourage all infected people to learn their status and start …
Two Zika vaccine candidates have shown promising results in pre-clinical trials, scientists have announced. A single shot of either vaccines appeared effective in protecting mice from an infection, in the weeks that followed immunisation. On 1 February 2016, the World Health Organisation declared Zika a public health emergency of international …
Australian researchers believe they've cracked the code which could lead to keeping the dreaded herpes virus, which causes cold sores, at bay for good. The herpes simplex virus (HSV) is known to remain dormant in an infected person's nerve cells long after any cold sores have healed, and scientists at …
A single dose of an experimental vaccine can protect mice against the Zika virus, raising renewed hope of a vaccine for humans, say scientists. The US team say the results, published in Nature, are "striking" and should "galvanise" research efforts. Tests in humans could begin in months. But even if …
About 5.7 million Americans have heart failure, half of whom will die from the disease within 5 years, according to the Centers for Disease Control and Prevention (CDC). Two processes help drive the disease: a weakened heart muscle that is less able to pump, and the death of heart cells …
A new small study showed that a certain human antibody, which already has the potential to protect people against Human Immunodeficiency Virus, can help suppress viral rebound in HIV-positive patients who have stopped taking antiretroviral drugs. The study, published in the journal Nature, revealed that injecting a neutralizing antibody called …
Zika virus is a member of the flavivirus genus that had not been associated with severe disease in humans until the recent outbreaks, when it was linked to microcephaly in newborns in Brazil and to Guillain-Barré syndrome in adults in French Polynesia.
The first Phase-1 human clinical trial of a vaccine for the Zika virus is set to begin in the coming weeks, with the U.S. Food and Drug Administration (FDA) green-lighting it. The DNA vaccine (GLS-5700) developed by the U.S-based Inovio Pharmaceuticals and GeneOne Life Science, South Korea, has already been …
LONDON – Tanaka Kikinzoku Kogyo K.K. said it has developed a reagent that can drastically shorten the time to detect Zika virus infections, which are spreading mainly in Brazil. The reagent needs only 10 to 15 minutes to determine whether suspected carriers are infected, while the current method requires special …
The flaviviruses dengue virus (DENV) and Zika virus (ZIKV) are severe health threats with rapidly expanding ranges. To identify the host cell dependencies of DENV and ZIKV, we completed orthologous functional genomic screens using RNAi and CRISPR/ Cas9 approaches. The screens recovered the ZIKV entry factor AXL as well as …
Diverse antibodies induced in humans by vaccination with an avian influenza virus vaccine may offer broader, more durable protection against multiple strains of influenza than today's vaccines typically provide, according to a study led by Florian Krammer, PhD, Assistant Professor in the Department of Microbiology at the Icahn School of …
A new vaccine allows pneumonia-causing bacteria to colonize inside the body, springing into action only if the bacteria pose a threat. The breakthrough approach, coupled with the protein-based vaccine's potential to counteract more than 90 strains of the bacteria, has the makings to override how vaccines have worked (destroying bacteria …
Alternative splicing (AS) defects that adversely affect gene expression and function have been identified in diabetic hearts; however, the mechanisms responsible are largely unknown. Here, we show that the RNA-binding protein RBFOX2 contributes to transcriptome changes under diabetic conditions. RBFOX2 controls AS of genes with important roles in heart function …
UK scientists have developed a blood test to help doctors pick the best drug for patients with depression. Medics currently have to rely on trial and error, meaning around half of the time the first type of antidepressant given fails to work. The researchers from King's College London say checking …
Researchers at the Institute for Systems Biology and Center for Infectious Disease Research in Seattle have deciphered how the human pathogen Mycobacterium tuberculosis is able to tolerate the recently approved FDA drug bedaquiline. The study demonstrated that silencing certain regulatory genes in the bacteria, or pairing with a second drug …
Malaria parasites cause hundreds of millions of infections, and kills hundreds of thousands of people annually, mostly in Africa. And in recent years the most dangerous malaria parasite, Plasmodium falciparum, has become increasingly resistant to the main anti-malarial drugs. Now, an international team of researchers shows that some members of …
The successful results of a University of Liverpool led drug trial aimed at developing new therapeutic approaches to cancer have been presented at two American medical conferences. The drug trial (APR-246) aimed to test the effects of a novel compound on a specific protein, p53, found to be mutated in …
Dishman Pharma Poonam Khetrapal Singh said in India, we would need to think of new ways in which the health care services are rendered. Laying stress on promoting research work in pharmaceutical sector, Regional Director of WHO South East Asia, Poonam Khetrapal Singh said India needs to incorporate changes and …
