Medical Research

Order of the National Green Tribunal regarding deterioration of Nayar river, Uttarakhand, 05/06/2025

Order of the National Green Tribunal in the matter of In Re: News Item titled "Nayar river is vanishing - a yatra reveals conservation goes beyond science and policy" appearing in ‘The Down To Earth’ dated 03.06.2025. The original application was registered suo-motu based on the news item titled "Nayar …

New drug alternatives

A TIENTS who do not respond to AZT -the primary AIDS therapeutic drug produced and patented almo worldwide by Burroughs Wellcome Co -now have hope. Studies at the US Nationi Institutes of Health at Bethesd Maryland, show two other drugs . le DDC produced by Hoffmann at Roche Inc and …

Mapping mosquitoes

RESEARCHERS in New York have given a fillip to the fight against malaria by breaking into the genes of the parasite. The scientists report they have made test-tube clones of the 14 chromosomes, which contain the genes of the microbe that mosquitoes transmit to humans. They have also shown the …

Agony and ecstasy

IF YOU thought headaches were restricted to reluctant Mills and Boons heroines, think again. After a 14-year follow-up study of 26 patients, scientists John R Ostergaard and Morten Kraft from the University Hospital of Arhus and the Private Clinic of Neurology in Denmark report a number of men and women …

Laboratory made antibodies work miracles

A REVOLUTION is taking place in medical immunology with the discovery of a method to produce monoclonal antibodies, which offer a powerful and less toxic treatment for diverse diseases, from cancer to rheumatoid arthritis, than most available drugs (British Medical Journal, Vol 340, Nos 6864-6). In the mid-1970s, a group …

Protein provides clue to Alzheimer`s disease

WHEN HARVARD researchers Bruce Yankner and Neil Kowall discovered in 1991 that amyloids -- small proteins -- injected into the brain of rats could destroy nerve cells in the same manner as observed in Alzheimer's patients, there was much excitement. Alzheimer's disease is the fourth largest killer in the developed …

Arthritic relief

SCIENTISTS at Cambridge University's Department of Pathology have found an effective way of treating patients with long-standing rheumatoid arthritis, using "humanised monoclonal antibodies". Produced from animal cells, monoclonal antibodies are designed to order and can kill unwanted cells. Mainly used to treat cancer, these antibodies are now being used to …

No monkeying around

FINALLY, an AIDS vaccine that works -- on monkeys. Harvard University researchers in despair turned to the old-fashioned, but unsafe, method and injected four rhesus monkeys with a weakened, live form of SIV, the virus that causes AIDS in primates. The researchers reported that the vaccine immunised the monkeys with …

Vaccine for dengue

A SAFE vaccine against dengue and dengue haemorrhagic fever has been developed by scientists at Bangkok's Mahidol University, who have been working on a WHO-sponsored research programme for the last 13 years. Dengue is transmitted by the bite of the infective Aedes aegypti mosquito and is caused by the dengue …

Serum found to curb lung cancer

SCIENTISTS say a vaccine for human lung cancers may be ready soon, allowing a therapeutic cure for the disease. Lung cancer is characterised by an abnormal production of hormones, particularly the human chorionic gonadotropin (HCG). Malignancy is indicated by high lev els of HCG and successful surgery in lung cancer …

Baboon liver for humans

A 35-YEAR-OLD man, the first person in the world to receive a baboon's liver, died after two months of the transplant. Though he was found to be HIV-infected, he had reportedly not developed AIDS. Surgeons at the University of Pittsburgh Medical Centre plan to continue experimental transplants as rejection of …

`Racist` conference

THE US National Institute of Health (NIH) has halted grant to a conference on 'Links between genetic disposition and criminal behaviour', following complaints that the conference might be a covert attack on African- Americans, who constitute 46 per cent of prisoners in USA. The conference on genetic factors in crime, …

Device Spots potential back pain

PHYSIOTHERAPY researchers in Australia have developed a device that can predict the probability of back pain in humans. Many devices can measure spinal muscle functions, such as strength and endurance, but the Australian device called the Pressure Biofeedback Unit (PBU), can calculate the supportive capacity of muscles that protect the …

Absent gene

STEWART Cole and his team of scientists at the Pasteur Institute in Paris have discovered that the absence of a single large gene is responsible for making certain strains of tuberculosis bacteria resistant to isoniazid, the principal drug used to treat the disease. (Nature, Vol 358, No 6387) On reinserting …

Caffeine could fight cancer

SCIENTISTS have good news for tea and coffee drinkers: they need not kick the habit for fear that the caffeine in the beverages causes cancer. Research indicates that caffeine may actually help prevent cancer caused by radiation and certain chemicals and that it can be useful in radiotherapy. Till 20 …

Perfecting crystals

THE GRAVITY-FREE environment in space will form more perfect crystals of certain proteins and scientists hope that by understanding their protein structure, they will be able to design better drugs to combat diabetes and arthritis, along with some other diseases. A protein derived from the deadly toxin found in castor …

Integrity at stake

THE MOST significant case on an issue of scientific integrity in recent times, that of AIDS researcher Robert Gallo, has yet to be settled. The Office of Scientific Integrity (OSI) of the National Institute of Health (NIH) cleared Gallo of misdemeanour early this year, (Down To Earth, July 31). Now, …

`Squeamish` attitudes hurts AIDS efforts

THE EIGHTH international conference on AIDS "will be sadly remembered for the change in venue from Boston to Amsterdam, necessitated by the discriminatory travel restrictions still in place in the USA". This rueful comment was made at the opening session by Michael Merson, director of WHO's global programme on AIDS, …

A new disease or an HIV mutant?

RESEARCHERS at the conference were divided over the dramatic disclosure of a disease similar to AIDS, which does not arise from the human immunodeficiency virus (HIV). This raised a debate on whether this was a new disease or had resulted from an HIV mutant. The virus responsible for this disease …

US scientist uses herpes virus to fight brain tumours in rats

SURGEONS may soon be able to call upon living micro-organisms to fight tumours that cannot be reached by the surgeon's scalpel. US scientists are proposing a new form of "molecular surgery" involving the transfer of a viral gene into the tumour and then attacking it with the anti-viral drug, ganciclovir. …

Gout gene

SCIENTISTS are now looking for a defective gene that leads to over-production of uric acid, a condition that may lead to gout-related disorders and kidney complaints. Recent research shows that gout is not confined to overweight, elderly people with a penchant for alcohol. Children can also develop gout and kidney …

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