Sleeping Sickness

Wastewater: turning problem to solution

Wastewater is a growing health and environmental threat, accounting for almost as many planet warming emissions as the aviation industry. Yet, with the right policies, wastewater could be an invaluable resource, providing alternative energy to half a billion people, supplying over 10 times the water provided by current global desalination …

Governing multisectoral action for health in low- and middle-income countries

he 2030 Agenda for Sustainable Development adopted by countries at the United Nations in 2015 sets forth a comprehensive vision of development with 17 Sustainable Development Goals (SDGs) and 169 targets across all aspects of society [1]. The 2030 Agenda document is ambitious and explicit about the need for integrated …

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

Chagas disease, leishmaniasis and sleeping sickness affect 20 million people worldwide and lead to more than 50,000 deaths annually. The diseases are caused by infection with the kinetoplastid parasites Trypanosoma cruzi, Leishmania spp. and Trypanosoma brucei spp., respectively. These parasites have similar biology and genomic sequence, suggesting that all three …

E-reading at night can leave you sleepless

Use of a light-emitting electronic device such as e-books in the hours before bedtime can adversely impact sleep, overall health, alertness and the circadian clock, a new study has found. Researchers at Brigham and Women's Hospital (BWH) compared the biological effects of reading a light-emitting electronic device (LEeBook) compared to …

International Glossina Genome Initiative 2004–2014: A driver for post-genomic era research on the African continent

Human African trypanosomiasis (HAT), also known as sleeping sickness, is a neglected disease that impacts 70 million people distributed over 1.55 million km2 in sub-Saharan Africa and includes at least 50% of the population of the Democratic Republic of the Congo. Trypanosoma brucei gambiense accounts for more than 98% of …

Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African Trypanosomiasis

Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous reproduction, and lactation. Here, we describe the sequence and annotation …

Human African Trypanosomiasis Research Gets a Boost: Unraveling the Tsetse Genome

Human African trypanosomiasis (HAT), also known as sleeping sickness, is a neglected disease that impacts 70 million people distributed over 1.55 million km2 in sub-Saharan Africa. Trypanosoma brucei gambiense accounts for almost 90% of the infections in central and western Africa, the remaining infections being from T. b. rhodesiense in …

Sleeping Sickness Epidemics and Colonial Responses in East and Central Africa, 1900–1940

Human African trypanosomiasis, better known as sleeping sickness, nowadays ranks among the more neglected diseases in the countries of Africa where it is found. Though it still kills many people every year, it cannot compete for celebrity with such major killers as malaria and AIDS. Yet that was not always …

Sleepless nights can shrink human brain'

In a finding that could lead to new treatment for insomnia, a new study has claimed that sleeplessness may actually shrink a person's brain. The University of Cam- bridge study -- the first to link insomnia to a reduction in vital grey matter -- showed that those with chronic sleep …

A parasites pantomime

How the sleeping sickness protozoan evades capture history provides examples of robbers who were masters at disguise. Charles Peace of 19th century England was one. A scholarly gentleman during the day and a burglar by nightfall, he embarrassed even the Scotland Yard at its inability to apprehend him. Science provided …

Chasing Sleep

Tired all the time, nodding off in the Sounds like you? Better check out. Experts say, millions of Indians need to catch up with their sleep. How to sleep right and enough Sleeping next to a man snoring through the night is bad enough. But when one night his wife …

Fighting flies with fancy

RESEARCHERS in Zimbabwe have found an effective way to deal with tsetse flies. The novel solution, which is simple, cost-effective, efficient and environ- ment-friendly, was first devised by the Rekomitjie research station in the Zambezi Valley in northern Zimbabwe. The research team discovered that tsetse flies are attracted by both …

Panacea for insomniacs

For those who toss and turn in bed hoping for at least a wink of sleep, here is some good news. Scientists from the Scripps Research Institution at La Jolla, California, US, have just synthesised certain new chemicals that would coax the human brain into slumber. Conventional sleeping pills that …

Sick of sleep

FROM darkness we come and into darkness we go, but in between this a mysterious darkness ebbs in and out of our lives every 24 hours, rejuvenating us for the struggles of the day. But for some 20 million Americans suffering from obstructive sleep apnea, this biological necessity called sleep …

Sleeping with the malady

IF YOU are a heavy snorer, with bouts 0( stopped breathing during sleep, you could be putting your heart to increased risk of diseases. Researchers concluded recently that the seemingly harmless phenomenon of interruptions during sleep called apnea, plays an insidious role in causing heart diseases, in~luding congestive heart failure, …

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