Medical Research

Order of the National Green Tribunal regarding deterioration of Nayar river, Uttarakhand, 05/06/2025

Order of the National Green Tribunal in the matter of In Re: News Item titled "Nayar river is vanishing - a yatra reveals conservation goes beyond science and policy" appearing in ‘The Down To Earth’ dated 03.06.2025. The original application was registered suo-motu based on the news item titled "Nayar …

Complement and antibody-mediated enhancement of red blood cell invasion and growth of malaria parasites

Plasmodium falciparum malaria is a deadly pathogen. The invasion of red blood cells (RBCs) by merozoites is a target for vaccine development. Although anti-merozoite antibodies can block invasion in vitro, there is no efficacy in vivo. To explain this discrepancy we hypothesized that complement activation could enhance RBC invasion by …

Association of p53 codon72 Arg>Pro polymorphism with susceptibility to nasopharyngeal carcinoma: evidence from a case–control study and meta-analysis

Tumor suppressor p53 is a critical player in the fight against cancer as it controls the cell cycle check point, apoptotic pathways and genomic stability. It is known to be the most frequently mutated gene in a wide variety of human cancers. Single-nucleotide polymorphism of p53 at codon72 leading to …

Ascorbic acid co-administration with artemisinin based combination therapies in falciparum malaria

Malaria infection poses a serious public health problem in endemic countries. As per World Malaria Report 2015, it is estimated that 3.2 billion people in 97 countries are at risk of being infected with malaria; 214 million cases of malaria with 4,38,000 malaria induced deaths are reported during the year …

Scientists edge closer to growing blood stem cells in lab

Significant progress has been made in working out how to grow blood stem cells in a laboratory. Researchers have discovered the protein responsible for regulating the function and development of the cells, providing them with a "serious advantage" in working out how to maximise them for therapies. Blood stem cells …

Scientists turn skin cells into heart, brain cells using drugs

U.S. researchers said Thursday they turned skin cells into heart cells and brain cells using just a combination of chemicals, a breakthrough that may lay the foundation for one day regenerating lost or damaged cells with pharmaceutical drugs. All previous work on cellular reprogramming required adding external genes to the …

Antibody shields monkeys from HIV-like virus for months

Just one shot of a lab-produced antibody protected macaques against a sort of monkey HIV for nearly six months, said a study Wednesday into a potential vaccine alternative. Exposed to simian HIV (SHIV) once a week, non-treated monkeys contracted the virus after just three weeks on average, the researchers said, …

Danish researchers behind vaccine breakthrough

A Danish research team from the University of Copenhagen has designed a simple technique that makes it possible to quickly and easily develop a new type of vaccines. The simple and effective technique will pave the way for effective vaccines against not only infectious diseases but also cancer and other …

Revolutionary antibiotics will save the world

An international team of including the Lomonosov Moscow State University researchers discovered which enzyme enables Escherichia coli bacterium (E. coli) to breathe. The study is published in the Scientific Reports. Scientists discovered how the E. coli bacterium can survive in the human gut - earlier the question how they breathe …

In search of vaccines against malaria

It is generally believed that an efficacious vaccine will be a major asset and the most cost-effective intervention in combating malaria. The fact that individuals living in malaria endemic areas develop immunity against the disease and that injection of irradiated sporozoites can protect humans from infection, suggest that it may …

ISRO’s rocket technology to power human hearts

Rocket science may not be able to fix broken hearts, but very soon technology mastered at the Indian Space Research Organisation (ISRO) may be able to help patients who are in need for a heart transplant. Materials and mechanisms used on Indian rockets have been tweaked by ISRO to make …

Final piece of type 1 diabetes puzzle solved

A complete picture of the areas that the immune system attacks to cause type 1 diabetes has finally been revealed by scientists. The study, published in the journal Diabetes, discovered the fifth and final critical target at which the immune system errantly takes aim. The team at the University of …

This tiny device is 12 times more effective at treating pancreatic cancer

A small, implantable device could transform the treatment of pancreatic cancer, with researchers announcing that in tests carried out on mice, the thin film was up to 12 times more effective than standard chemotherapy treatments, which usually involve the intravenous injection of drugs. Part of the problem in tackling pancreatic …

Antimalarial resistance to drug unable to spread by mosquitoes: study

In a study they might be helpful for malaria control, scientists said Thursday that resistance to the antimalarial drug atovaquone cannot be passed on by mosquitoes. Atovaquone was introduced in 2000 and is safe for pregnant women and children, but it was largely phased out of use because resistance was …

Gene editing 'boosts' cancer-killing cells

Cancer scientists have genetically modified the immune system to help it attack tumours in mice. The immune system is the body's own defence against infection and cancer, but tumours develop ways of stopping the onslaught. The University College London team manipulated the DNA of immune cells to allow them to …

No clinical trials for ayurvedic drugs: Haryana

Chandigarh: The Haryana government has told the Punjab and Haryana high court that 'there is no protocol for clinical trials of ayurvedic drugs' even as it administers ayurvedic medicines to drug addicts. Justice Rajive Bhalla, who has since retired from the high court, had asked Haryana in October 2015 about …

Cholesterol drug fails to improve heart health: study

An experimental drug that greatly increases levels of "good" cholesterol has no effect on heart health, a comprehensive clinical trial found, leaving researchers shocked and disappointed. It is also a blow to patients who were hoping for an alternative because they cannot or will not take statins, which can cut …

Researchers find 'simple' methods to prevent heart attacks and stroke worldwide

Three simple solutions to prevent heart attacks and stroke worldwide have been proven effective by an international team led by Hamilton medical researchers. The research team from the Population Health Research Institute (PHRI) of McMaster University and Hamilton Health Sciences studied more than 12,000 patients from 21 countries to evaluate …

Japanese research team grows skin organ in mice using iPS cells

Japanese scientists said Saturday they have bioengineered the skin organ known as the integumentary system in mice using induced pluripotent stem (iPS) cells. The achievement is likely to lead to further progress in regenerative medicine to treat severe burns, skin diseases and hair loss as the organ contains all the …

Oxytocin, functions, uses and abuses: A brief review

Oxytocin a peptide hormone has the distinction of being the first among the peptide hormones to be sequenced and biochemically synthesized. Oxytocin is secreted from neural as well as non-neural sources inside the body. Among the neural sources supra-optic and paraventricular nuclei of the brain are major sources of secretion, …

Zika virus structure revealed, a critical advance in the development of treatments

A team led by Purdue University researchers is the first to determine the structure of the Zika virus, which reveals insights critical to the development of effective antiviral treatments and vaccines. The team also identified regions within the Zika virus structure where it differs from other flaviviruses, the family of …

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