Diagnostic Methods

Order of the National Green Tribunal regarding dumping yard at Baliapanda, Puri district, Odisha, 24/03/2025

Order of the National Green Tribunal (Eastern Zone Bench, Kolkata) in the matter of Haripriya Patel Vs State of Odisha & Others dated 24/03/2025. The matter related to the dumping yard at Baliapanda which is situated 50-100 meter away from Puri sea beach and a few km away from Puri …

WHO’s new End TB Strategy

On May 19, 2014, the 67th World Health Assembly (WHA) adopted WHO’s “Global strategy and targets for tuberculosis prevention, care and control after 2015”. This post-2015 global tuberculosis strategy, labelled the End TB Strategy, was shaped during the past 2 years. A wide range of stakeholders—from ministries of health and …

The End TB Strategy: India can blaze the trail

In spite of significant progress made in tuberculosis (TB) control, nine million people developed TB disease in 2013, and 1.5 million died of TB. While implementation of the Stop TB (DOTS) Strategy has cured millions of patients with TB, and undoubtedly saved lives, the impact of this strategy on reducing …

Modelling the effect of early detection of Ebola

Almost 20 000 cases of Ebola virus disease have been reported in west Africa. Estimates of the reproductive ratio of the outbreak suggest that about half of infectious contacts need to be prevented to control the epidemic. The international response in the affected regions has focused mainly on establishing infrastructure …

Treatment of infections in young infants in low- and middle-income countries: A systematic review and meta-analysis of frontline health worker diagnosis and antibiotic access

Neonatal mortality—death that occurs during the first 28 days of life—accounts for nearly half of all the deaths that occur in children before they reach their fifth birthday. Worldwide, nearly 3 million neonatal deaths occur every year. Three bacterial infections—sepsis (infection of the bloodstream), pneumonia (infection of the lungs), and …

Evaluation of commercially available diagnostic tests for the detection of dengue virus NS1 antigen and Anti-Dengue virus IgM antibody

Dengue virus (DENV) infection occurs throughout tropical and sub-tropical regions of the world where dengue is a major public health problem. Laboratory diagnosis of dengue with a single serum specimen obtained during the acute phase of the illness requires tests to detect IgM antibodies to DENV or the virus genome. …

Mild hypertension in people at low risk

Measurement of blood pressure is an iconic part of modern medicine. Over the past century, life insurers, public health organisations, and prospective studies, including the Framingham Heart Study, have established the relation between increased blood pressure and long term morbidity and mortality. About 40% of adults have hypertension globally; the …

Effect of implementation of the mass breast cancer screening programme in older women in the Netherlands: population based study

Breast cancer is the largest contributor to cancer incidence and cancer mortality in women worldwide. As people in Western societies are living longer, there will be an increase in the proportion of older women with breast cancer in upcoming years. Older women with breast cancer often have comorbidities and functional …

Early therapy for type 2 diabetes in China

Diabetes is a huge burden in China, where about 100 million people have been diagnosed with the disease. Treatments are needed that are optimal for treating Chinese patients with diabetes. Chinese patients with type 2 diabetes are characterised by having relatively low bodyweight and significant β-cell deterioration. β-cell failure results …

Clinical management of concurrent diabetes and tuberculosis and the implications for patient services

Diabetes triples the risk for active tuberculosis, thus the increasing burden of type 2 diabetes will help to sustain the present tuberculosis epidemic. Recommendations have been made for bidirectional screening, but evidence is scarce about the performance of specific tuberculosis tests in individuals with diabetes, specific diabetes tests in patients …

Recurrent outbreaks of hypoglycaemic encephalopathy in Muzaffarpur, Bihar

Earlier we had reported that the recurring annual seasonal outbreaks in Muzaffarpur district, Bihar, of what used to be considered viral encephalitis and called 'acute encephalitis syndrome' since no virus could be detected, is acute encephalopathy. Our report was based on a limited study and retrospective analysis of case records. …

Burden of childhood tuberculosis in 22 high-burden countries: A mathematical modelling study

Confirmation of a diagnosis of tuberculosis in children (aged <15 years) is challenging; under-reporting can result even when children do present to health services. Direct incidence estimates are unavailable, and WHO estimates build on paediatric notifications, with adjustment for incomplete surveillance by the same factor as adult notifications. We …

The importance of implementation strategy in scaling up Xpert MTB/RIF for diagnosis of Tuberculosis in the Indian health-care system: A transmission model

ndia has announced a goal of universal access to quality tuberculosis (TB) diagnosis and treatment. A number of novel diagnostics could help meet this important goal. The rollout of one such diagnostic, Xpert MTB/RIF (Xpert) is being considered, but if Xpert is used mainly for people with HIV or high …

Question raised in Rajya Sabha on rise in MDR TB cases, 15/07/2014

Question raised in Rajya Sabha on rise in MDR TB cases, 15/07/2014.

HIV prevention, diagnosis, treatment and care for key populations - Consolidated guidelines

The new consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations bring together all existing World Health Organization (WHO) guidance relevant to five key populations (both adults and adolescents) in the HIV response: men who have sex with men, people who inject drugs, people in prisons and …

Burden of childhood tuberculosis in 22 high-burden countries: a mathematical modelling study

Confirmation of a diagnosis of tuberculosis in children (aged <15 years) is challenging; under-reporting can result even when children do present to health services. Direct incidence estimates are unavailable, and WHO estimates build on paediatric notifications, with adjustment for incomplete surveillance by the same factor as adult notifications. We …

Question raised in Rajya Sabha deaths from encephalitis in Bihar, 08/07/2014

Question raised in Rajya Sabha deaths from encephalitis in Bihar, 08/07/2014.

Public health at risk: 6000 unregistered collection centres in Kashmir

Posing a huge threat to the public health, nearly 6000 unregistered collection centres are functional in Kashmir Valley. The collection centers are opened at various pharmacies and clinics of doctors. The samples for various blood and related tests are collected at these centres and mostly send outside Kashmir for examinations. …

Communicating and monitoring surveillance and response activities for malaria elimination: China's “1-3-7” strategy

Taking a malaria control program from the control phases through to elimination is challenging. The reorientation of the malaria control program involves a shift of focus, from reaching high levels of coverage of interventions to prevent morbidity and mortality, to an emphasis on completeness and timeliness of activities in order …

Ebola — A growing threat?

The recent emergence of Zaire ebolavirus in West Africa has come as a surprise in a region more commonly known for its endemic Lassa fever, another viral hemorrhagic fever caused by an Old World arenavirus. Yet the region has seen previous ebolavirus activity. In the mid-1990s, scientists discovered Côte d'Ivoire …

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