Order of the Supreme Court of India in the matter of Network of People Living With HIV/AIDS & Others Vs Union of India & Others dated 24/02/2025. The Supreme Court (SC), February 24, 2025 has directed all states to file their affidavits addressing concerns raised about antiretroviral therapy (ART) drugs …
Kampala — Ugandan scientists have developed a drug from natural herbs that can cure malaria in about three days. According to a study released by the scientists, the drug, DEI Anti-malaria, can kill malaria-causing parasites within the human body using its natural compounds extracted from plants. The lead-investigator, Dr Patrick …
Little information is available about the effect of pneumococcal conjugate vaccines (PCVs) in low-income countries. We measured the effect of these vaccines on invasive pneumococcal disease in The Gambia where the 7-valent vaccine (PCV7) was introduced in August, 2009, followed by the 13-valent vaccine (PCV13) in May, 2011. Original Source
Artemisinin-based therapies are the only effective treatment for malaria, the most devastating disease in human history. To meet the growing demand for artemisinin and make it accessible to the poorest, an inexpensive and rapidly scalable production platform is urgently needed. Here we have developed a new synthetic biology approach, combinatorial …
Deaths caused by AIDS declined nearly 55% in India in the past eight years, whereas new HIV infections came down by 66% since 2000. In 2007, India had recorded 1,48,309 such deaths; in 2015, the figure stood at just 67,600, according to latest statistics presented by health minister J P …
Diverse antibodies induced in humans by vaccination with an avian influenza virus vaccine may offer broader, more durable protection against multiple strains of influenza than today's vaccines typically provide, according to a study led by Florian Krammer, PhD, Assistant Professor in the Department of Microbiology at the Icahn School of …
This report provides guidance for countries to enhance the functioning and transparency of the patent system for the timely and affordable access to lifesaving treatment. Affordable access to treatment is closely linked with the aspiration to ensure health and well-being for all, as embodied in the Sustainable Development Goal (SDG). …
Products of major pharmaceutical firms, including Abbott Healthcare, Cipla and Lupin will be affected by the new price cap Prices of 56 important medicines used in treatment of cancer, diabetes, bacterial infections and blood pressure have been capped by the government, thereby reducing the cost by an average of nearly …
Researchers at the Institute for Systems Biology and Center for Infectious Disease Research in Seattle have deciphered how the human pathogen Mycobacterium tuberculosis is able to tolerate the recently approved FDA drug bedaquiline. The study demonstrated that silencing certain regulatory genes in the bacteria, or pairing with a second drug …
Malaria parasites cause hundreds of millions of infections, and kills hundreds of thousands of people annually, mostly in Africa. And in recent years the most dangerous malaria parasite, Plasmodium falciparum, has become increasingly resistant to the main anti-malarial drugs. Now, an international team of researchers shows that some members of …
The successful results of a University of Liverpool led drug trial aimed at developing new therapeutic approaches to cancer have been presented at two American medical conferences. The drug trial (APR-246) aimed to test the effects of a novel compound on a specific protein, p53, found to be mutated in …
WASHINGTON - Two Israeli companies say they used a specialized 3-D printer to create an environment in which stem cells could grow into a specific tissue. In the near future, the technology could be used for testing new drugs, but it also opens up the possibility of growing organ replacements. …
MUMBAI: Increase in patents on essential medicines in India will jeopardise supply of affordable treatment , not only in the country, but also in developing nations. The latest trigger raising concerns among public health advocates is exorbitantly-priced hepatitis C drug sofosbuvir by Gilead, which was recently granted a patent in …
A research team at Duke University has discovered a potential new class of small-molecule drugs that simultaneously block two sought-after targets in the treatment of pain. These proof-of-concept experiments, published June 1 in Scientific Reports, could lead to the development of a new drug to treat conditions including skin irritation …
New hepatitis C virus (HCV) medicines have markedly improved treatment efficacy and regimen tolerability. However, their high prices have limited access, prompting wide debate about fair and affordable prices. This study systematically compared the price and affordability of sofosbuvir and ledipasvir/sofosbuvir across 30 countries to assess affordability to health systems …
Melbourne researchers have discovered a new way of triggering cell death, in a finding that could lead to drugs to treat cancer and autoimmune disease. Programmed cell death, also called apoptosis, is a natural process that removes unwanted cells from the body. Failure of apoptosis can allow cancer cells to …
Among the several new antimalarials discovered over the past decade are at least three clinical candidate drugs, each with a distinct chemical structure, that disrupt Na+ homeostasis resulting in a rapid increase in intracellular Na+ concentration ([Na+]i) within the erythrocytic stages of Plasmodium falciparum. At present, events triggered by Na+ …
US biochemical engineer Frances Arnold gives a speech to accept the Millennium Technology Prize 2016 during the award ceremony in Helsinki, Finland, on May 24, 2016. Arnold won the million-euro technology prize for her work on "directed evolution". AMERICAN biochemical engineer Frances Arnold, whose discoveries in “directed evolution” have helped …
An Ebola clinical vaccine trial will be launched this July by the Kenya Medical Research Institute (KEMRI), the Standard Digital of Kenya reports. According to Senior Deputy Director of the KEMRI Walter Reed project, Dr Fredric Sawe, the effort by KEMRI is meant to restore the West African region which …
Two months after the Union health ministry launched a miracle drug for tuberculosis, Bedaquiline, with great pomp and show, the drug has not been put to use on a single patient. While the drug is available at the six sites shortlisted by the government, experts are waiting for the “ …
Leading upto International Clinical Trials Day, which falls on May 20, Suneela Thatte, President, Indian Society for Clinical Research (ISCR), is hopeful that new orders and revised guidelines will herald a renewed wave of progress in India’s clinical research scenario The last three years saw a drop in clinical research …
