Vector Control

Order of the National Green Tribunal regarding the deplorable condition of a water tank, Golconda Fort, Hyderabad, Telangana, 05/06/2025

Order of the National Green Tribunal in the matter of In Re: News Item Titled "Neglected Katora Houz in Hyderabad’s Golconda Fort Cries for attention appearing in ‘The Siasat Daily’ dated 25 May 2025". The application was registered suo-motu based on the news item titled “Neglected Katora Houz in Hyderabad’s …

A malaria risk map of Kinshasa, Democratic Republic of Congo

In Kinshasa, malaria remains a major public health problem but its spatial epidemiology has not been assessed for decades now. The city’s growth and transformation, as well as recent control measures, call for an update. To identify highly exposed communities and areas where control measures are less critically needed, detailed …

Strategies and approaches to vector control in nine malaria-eliminating countries: a cross-case study analysis

There has been progress towards malaria elimination in the last decade. In response, WHO launched the Global Technical Strategy (GTS), in which vector surveillance and control play important roles. Country experiences in the Eliminating Malaria Case Study Series were reviewed to identify success factors on the road to elimination using …

Judgement of the National Green Tribunal regarding industries involved in the illegal sale of hazardous waste materials to the public, Karur, Tamil Nadu, 15/12/2015

Judgement of the National Green Tribunal (Southern Zone, Chennai) in the matter of M/s. Tamil Nadu HDPE Knitted Fabrics Manufacturers Association Vs Central Insecticides Board and Registration Committee & Others dated 15/12/2015 regarding certain industries involved in the illegal sale of hazardous waste materials to the public by misusing the …

Three-month real-time Dengue forecast models: An early warning system for outbreak alerts and policy decision support in Singapore

With a tropical rainforest climate, rapid urbanization, changing demography and ecology, Singapore experiences endemic dengue, with the last large outbreak in 2013 culminating in 22170 cases. In the absence of a vaccine on the market, vector control is the key approach for prevention. The objective of the study was to …

World Malaria Report 2015

New estimates from WHO show a significant increase in the number of countries moving towards malaria elimination, with prevention efforts saving millions of dollars in healthcare costs over the past 14 years in many African countries. According to the "World Malaria Report 2015", more than half (57) of the 106 …

Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi

Malaria continues to impose enormous health and economic burdens on the developing world. Novel technologies proposed to reduce the impact of the disease include the introgression of parasite-resistance genes into mosquito populations, thereby modifying the ability of the vector to transmit the pathogens. Such genes have been developed for the …

Plasmodium P-Type cyclin CYC3 modulates endomitotic growth during oocyst development in mosquitoes

Cell-cycle progression and cell division in eukaryotes are governed in part by the cyclin family and their regulation of cyclin-dependent kinases (CDKs). Cyclins are very well characterised in model systems such as yeast and human cells, but surprisingly little is known about their number and role in Plasmodium, the unicellular …

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

Since the year 2000, a concerted campaign against malaria has led to unprecedented levels of intervention coverage across sub-Saharan Africa. Understanding the effect of this control effort is vital to inform future control planning. However, the effect of malaria interventions across the varied epidemiological settings of Africa remains poorly understood …

Induction of multidrug tolerance in Plasmodium falciparum by extended Artemisinin pressure

Plasmodium falciparum resistance to artemisinin derivatives in Southeast Asia threatens global malaria control strategies. Whether delayed parasite clearance, which exposes larger parasite numbers to artemisinins for longer times, selects higher-grade resistance remains unexplored. We investigated whether long-lasting artemisinin pressure selects a novel multidrug-tolerance profile. Although 50% inhibitory concentrations for antimalarial …

Order of the National Green Tribunal regarding measures to prevent mosquito breeding, Delhi, 01/10/2015

Order of the National Green Tribunal (Principal Bench, New Delhi) in the matter of Kalindi Residents Welfare Association (KRWA) Vs. Union of India & Ors. dated 01/10/2015 regarding measures to prevent mosquito breeding, Delhi.

Associations between urbanicity and malaria at local scales in Uganda

Sub-Saharan Africa is expected to show the greatest rates of urbanization over the next 50 years. Urbanization has shown a substantial impact in reducing malaria transmission due to multiple factors, including unfavourable habitats for Anopheles mosquitoes, generally healthier human populations, better access to healthcare, and higher housing standards. Statistical relationships …

Deadly mosquito bites

As Delhi and other parts of the country battle the surge in dengue cases, here is a look at how vector-borne diseases have been spreading their tentacles over the years.

A candidate dengue vaccine walks a tightrope

The most advanced candidate vaccine against dengue viruses, called CYD-TDV, is progressing toward potential registration and review by the World Health Organization (WHO) in 2016. CYDTDV is a formulation of four chimeric yellow fever 17D vaccine viruses, each one engineered to express the surface envelope and prM (membrane) proteins from …

Efficacy and long-term safety of a dengue vaccine in regions of endemic disease

A candidate tetravalent dengue vaccine is being assessed in three clinical trials involving more than 35,000 children between the ages of 2 and 16 years in Asian–Pacific and Latin American countries. The researchers report the results of long-term follow-up interim analyses and integrated efficacy analyses.

An outbreak of Chikungunya in rural Bangladesh, 2011

The first identified Chikungunya outbreak occurred in Bangladesh in 2008. In late October 2011, a local health official from Dohar Sub-district, Dhaka District, reported an outbreak of undiagnosed fever and joint pain. We investigated the outbreak to confirm the etiology, describe the clinical presentation, and identify associated vectors. Original Source

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, …

The efficacy and safety of the RTS,S/AS01 candidate malaria vaccine during 18 months of follow-up have been published previously. Herein, we report the final results from the same trial, including the efficacy of a booster dose.

DDT-based indoor residual spraying suboptimal for visceral leishmaniasis elimination in India

Indoor residual spraying (IRS) is used to control visceral leishmaniasis (VL) in India, but it is poorly quality assured. Quality assurance was performed in eight VL endemic districts in Bihar State, India, in 2014. Residual dichlorodiphenyltrichloroethane (DDT) was sampled from walls using Bostik tape discs, and DDT concentrations [grams of …

Prospects for malaria elimination in Mesoamerica and Hispaniola

Malaria remains endemic in 21 countries of the American continent with an estimated 427,000 cases per year. Approximately 10% of these occur in the Mesoamerican and Caribbean regions. During the last decade, malaria transmission in Mesoamerica showed a decrease of ~85%; whereas, in the Caribbean region, Hispaniola (comprising the Dominican …

Diurnally subperiodic filariasis among the Nicobarese of Nicobar district - epidemiology, vector dynamics & prospects of elimination

In India diurnally subperiodic filariasis (DspWB) is prevalent only in the Nicobar district of Andaman and Nicobar Islands. Studies undertaken at different points of time indicate that this form of filariasis is restricted to a small region in Nancowry group of islands where it is transmitted by mosquito Downsiomyia nivea, …

Investing to overcome the impact of neglected tropical diseases

This third WHO report on neglected tropical diseases urges affected countries to scale up their investment in tackling 17 neglected tropical diseases in order to improve the health and well-being of more than 1.5 billion people.

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