Climate hazards, including extreme heat, are associated with increased risks of developing complications that lead to adverse maternal and perinatal outcomes. These may include multiple causes of maternal and neonatal morbidity and mortality such as gestational diabetes, hyper tensive disorders of pregnancy, preterm birth, low birth weight and stillbirth. In …
IF YOUR heart is in the wrong place, perhaps a gene is responsible for it. Researchers have recently identified a gene that plays a major role in deciding whether the internal organs in mice should be assigned to the right or left of the body and this has initiated the …
AFTER ten years of frustrating toil, a band of gene-hunters from USA and the UK have at last nabbed the gene that causes Huntington's disease, a debilitating disorder of the nerves. The researchers are hopeful the discovery will provide a better understanding of what causes the nerves to degenerate, and …
FIVE-DAY-OLD Andrew Gobea became the first newborn to undergo gene therapy when surgeons at a Los Angeles hospital injected him recently with gene-altered cells obtained from his mother's placental blood to cure a usually fatal defect in his immune system. Andrew suffers from bubbly bay disease and lacks an enzyme …
WHEN HARVARD researchers Bruce Yankner and Neil Kowall discovered in 1991 that amyloids -- small proteins -- injected into the brain of rats could destroy nerve cells in the same manner as observed in Alzheimer's patients, there was much excitement. Alzheimer's disease is the fourth largest killer in the developed …
Fathers may be responsible for birth defects in their offspring (New Scientist, Vol 136 No 1843). Research using animal models suggests some miscarriages, birth defects and children's diseases can be blamed on the lifestyles and occupations of the fathers. Scientists thought sperm damaged by exposure to radiation or toxic chemicals …
SCIENTISTS are discovering that specialised structures in the minute world of cells do not float randomly from place to place but are actively transported along well laid out tracks by a veritable menagerie of motor molecules (Science, Vol 256 No 5065). The motor molecules play a fundamental role in the …
Information available on the present status of genetic diseases in India is relatively meagre, considering the number and varieties of its populations. Data, based mainly on those from uurban referral units, suggest that the incidence is fairly high with the preponderance of certain defects in particular areas and subpopulations. Original …
