Epidemiological Studies

State of the Climate in Asia 2024

The World Meteorological Organization’s State of the Climate in Asia 2024 report warns that the region is warming nearly twice as fast as the global average, driving more extreme weather and posing serious threats to lives, ecosystems, and economies. In 2024, Asia experienced its warmest or second warmest year on …

Strategies and approaches to vector control in nine malaria-eliminating countries: a cross-case study analysis

There has been progress towards malaria elimination in the last decade. In response, WHO launched the Global Technical Strategy (GTS), in which vector surveillance and control play important roles. Country experiences in the Eliminating Malaria Case Study Series were reviewed to identify success factors on the road to elimination using …

A case–control study of prenatal thallium exposure and low birth weight in China

Thallium (Tl) is a highly toxic heavy metal widely present in the environment. Case reports have suggested that maternal exposure to high levels of Tl during pregnancy is associated with low birth weight (LBW), but epidemiological data are limited. This study was designed to evaluate whether prenatal Tl exposure is …

Carcinogenicity of consumption of red and processed meat

In October, 2015, 22 scientists from ten countries met at the International Agency for Research on Cancer (IARC) in Lyon, France, to evaluate the carcinogenicity of the consumption of red meat and processed meat. The Working Group assessed more than 800 epidemiological studies that investigated the association of cancer with …

A novel locus of resistance to severe malaria in a region of ancient balancing selection

The high prevalence of sickle haemoglobin in Africa shows that malaria has been a major force for human evolutionary selection, but surprisingly few other polymorphisms have been proven to confer resistance to malaria in large epidemiological studies. To address this problem, we conducted a multi-centre genome-wide association study (GWAS) of …

The Endocrine Society’s second scientific statement on endocrine-disrupting chemicals

This Executive Summary to the Endocrine Society’s second Scientific Statement on environmental endocrinedisrupting chemicals (EDCs) provides a synthesis of the key points of the complete statement. The full Scientific Statement represents a comprehensive review of the literature on seven topics for which there is strong mechanistic, experimental, animal, and epidemiological …

Preventing suicide: A global imperative

Every 40 seconds a person dies by suicide somewhere in the world. “Preventing suicide: a global imperative” is the first WHO report of its kind. It aims to increase awareness of the public health significance of suicide and suicide attempts, to make suicide prevention a higher priority on the global …

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological …

The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age–sex groups, and countries. The GBD can be used to …

High cholesterol awareness, treatment, and control among Hispanic/Latinos: Results from the Hispanic community health study/Study of Latinos

The researchers assessed high cholesterol (HC) awareness, treatment, and control rates among US Hispanic/Latino adults and describe factors associated with HC awareness and management.

Ambient air pollution and adult asthma incidence in six European cohorts (ESCAPE)

Short-term exposure to air pollution has adverse effects among patients with asthma, but whether long-term exposure to air pollution is a cause of adult-onset asthma is unclear. The researchers aimed to investigate the association between air pollution and adult onset asthma.

Prevalence and transmission of Trypanosoma cruzi in people of rural communities of the high jungle of Northern Peru

Vector-borne transmission of Trypanosoma cruzi is seen exclusively in the Americas where an estimated 8 million people are infected with the parasite. Significant research in southern Peru has been conducted to understand T. cruzi infection and vector control, however, much less is known about the burden of infection and epidemiology …

Short term exposure to air pollution and stroke: systematic review and meta-analysis

Outdoor air pollution is an important risk factor for cardiovascular disease throughout the world, with particulate air pollution alone responsible for over three million deaths each year. Increases in concentrations of daily air pollution are associated with acute myocardial infarction and admission to hospital or death from heart failure. These …

Menopausal hormone use and ovarian cancer risk: individual participant meta-analysis of 52 epidemiological studies

Half the epidemiological studies with information about menopausal hormone therapy and ovarian cancer risk remain unpublished, and some retrospective studies could have been biased by selective participation or recall. We aimed to assess with minimal bias the effects of hormone therapy on ovarian cancer risk.

Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease …

The Lancet presents the most recent update on the global, regional, and national causes of death. Against a backdrop of increased global improvements in life-expectancy, death rates for some causes – including drug use and liver cancer – continue to rise. Up-to-date evidence on levels and trends for age-sex-specific all-cause …

Incense use and cardiovascular mortality among Chinese in Singapore: The Singapore Chinese Health Study

Incense burning is common in many parts of the world. Although it is perceived that particulate matter from incense smoke is deleterious to health, there is no epidemiologic evidence linking domestic exposure to cardiovascular mortality. The researchers examined the association between exposure to incense burning and cardiovascular mortality in the …

Childhood cancer and exposure to corona ions from power lines: an epidemiological test

We previously reported an association between childhood leukaemia in Britain and proximity of the child’s address at birth to high-voltage power lines that declines from the 1960s to the 2000s. We test here whether a ‘corona-ion hypothesis’ could explain these results. This hypothesis proposes that corona ions, atmospheric ions produced …

Transmission dynamics and control of Ebola virus disease (EVD): a review

The complex and unprecedented Ebola epidemic ongoing in West Africa has highlighted the need to review the epidemiological characteristics of Ebola Virus Disease (EVD) as well as our current understanding of the transmission dynamics and the effect of control interventions against Ebola transmission. Here we review key epidemiological data from …

Identifying exposure disparities in air pollution epidemiology specific to adverse birth outcomes

More than 147 million people in the US live in areas where pollutant levels are above regulatory limits and pose a risk to health. Most of the vast network of air pollutant monitors in the US are located in places with higher pollution levels and a higher density of pollutant …

Impact and cost-effectiveness of new tuberculosis vaccines in low- and middle-income countries

To aid in prioritizing the development of tuberculosis (TB) vaccines most likely to reach the 2050 TB elimination goal, we estimated the impact and cost-effectiveness of a range of vaccine profiles in low- and middle-income countries. Using mathematical modeling, we show that vaccines targeted at adolescents/adults could have a much …

Epidemiological dynamics of Ebola outbreaks

Ebola is a deadly virus that causes frequent disease outbreaks in the human population. Here, we analyse its rate of new introductions, case fatality ratio, and potential to spread from person to person. The analysis is performed for all completed outbreaks, and for a scenario where these are augmented by …

Origin and evolution of European community-acquired Methicillin resistant Staphylococcus aureus

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) was recognized in Europe and worldwide in the late 1990s. Within a decade, several genetically and geographically distinct CA-MRSA lineages carrying the small SCCmec type IV and V genetic elements and the Panton-Valentine leukocidin (PVL) emerged around the world. In Europe, the predominant CA-MRSA strain …

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