Drugs

Order of the Supreme Court regarding ART drugs for people living with HIV/AIDS, 24/02/2025

Order of the Supreme Court of India in the matter of Network of People Living With HIV/AIDS & Others Vs Union of India & Others dated 24/02/2025. The Supreme Court (SC), February 24, 2025 has directed all states to file their affidavits addressing concerns raised about antiretroviral therapy (ART) drugs …

Ebola-Like Virus Beaten by Tekmira Treatment in Study

Monkeys sickened by Marburg virus, an Ebola relative that kills in the same way and is equally as fatal, survived the disease after being treated with an experimental drug developed by Tekmira Pharmaceuticals Corp. (TKMR) The results, published today in the journal Science Translational Medicine, are the first to show …

Experimental Ebola drugs needed for 'up to 30,000 people'

Up to 30,000 people could have used experimental treatments or vaccines so far in the world's worst outbreak of Ebola currently plaguing West Africa, British scientists said on Wednesday. The calculation highlights the dilemma facing officials considering how to distribute the tiny quantities of unproven drugs that are likely to …

Ebola Virus Quarantine Sparks Clashes in Liberia

Liberian soldiers on Wednesday fired into a crowd of young men who were trying to escape a quarantine that cordoned off an Ebola-stricken neighborhood in the capital. The clash marks the most worrisome sign to date that a public-health crisis is fast becoming a security crisis in Liberia, a nation …

Scale up the supply of experimental Ebola drugs

Estimates of the probable impact of the outbreak show that existing stocks of potentially useful medicines are insufficient, says Oliver Brady.

Ethics, economics, and the use of Primaquine to reduce Falciparum Malaria transmission in asymptomatic populations

Following a decade of gains in malaria control, two divergent prospects are emerging: malaria elimination in many endemic countries, and spreading artemisinin-resistant P. falciparum undermining these gains. The potential benefits of malaria elimination are substantial, including the direct burden averted and economic growth through improved educational attainment and productivity; these …

Fever rising

IN EASTERN Sierra Leone the roads are unusually quiet. Checkpoints manned by heavily armed soldiers have blocked all movement to and from the districts of Kailahun and Kenema. The main road to Freetown, the capital, is travelled by just a few motorbikes and cars carrying supplies. In Kenema, a usually …

SC notice to Centre, states on cheaper generic drugs

The Supreme Court today sought the response of the Centre and states to a PIL seeking proper implementation of the National Health Policy 2002 aimed at ensuring availability of cheaper generic medicines to the poor. A Bench comprising Justices Dipak Misra and V Gopala Gowda issued notice asking them to …

Altering the intestinal microbiota during a critical developmental window has lasting metabolic consequences

Acquisition of the intestinal microbiota begins at birth, and a stable microbial community develops from a succession of key organisms. Disruption of the microbiota during maturation by low-dose antibiotic exposure can alter host metabolism and adiposity. We now show that low-dose penicillin (LDP), delivered from birth, induces metabolic alterations and …

WHO approves experimental Ebola drug

Spanish priest becomes 1st European to succumb to latest Ebola outbreak The World Health Organisation authorised on Tuesday the use of experimental drugs to fight Ebola as the death toll topped 1,000 and a Spanish priest became the first European to succumb to the latest outbreak. Japan aid agency pulls …

WHO backs use of experimental Ebola drugs in West Africa epidemic

Liberia says it plans to treat two infected doctors with an unproven Ebola medicine called ZMapp People infected in the West Africa Ebola outbreak can be offered untested drugs, the World Health Organisation said on Tuesday, but scarce supplies raise questions about who gets priority in the epidemic of the …

Ethical to use untested Ebola drugs, says WHO

Untested drugs can be used to treat patients infected with the Ebola virus, the World Health Organization says. The WHO said it was ethical in light of the scale of the outbreak and high number of deaths - over 1,000 people have died in west Africa.. The statement was made …

Filariasis study in 5 districts

Five districts in Kerala will be included in a monitoring and epidemiological assessment conducted as part of the World Health Organisaton (WHO)'s global programme to eliminate lymphatic filariasis. The study is being conducted in Ernakulam, Alappuzha, Kottayam, Kollam and Thrissur districts. The study is aimed to check the efficacy of …

Ebola Drug Panel Set by WHO to Weigh Unproven Drugs Use

The World Health Organization will convene a panel of medical ethicists next week to explore the use of experimental treatments for Ebola amid the worst outbreak of the disease on record. An experimental antibody cocktail developed by Mapp Biopharmaceutical Inc. was used to treat two infected American health workers whose …

US big-data health network launches aspirin study

One of the largest big-data experiments in health care has set its first research target. The leaders of the Patient-Centered Outcomes Research Institute (PCORI) in Washington DC voted on 29 July to focus the institute’s first clinical trial on the use of aspirin to prevent heart disease. The US$10-million pilot …

The conceptual imperfection of aquatic risk assessment tests: highlighting the need for tests designed to detect therapeutic effects of pharmaceutical contaminants

Standardized ecotoxicological tests still constitute the fundamental tools when doing risk-assessment of aquatic contaminants. These protocols are managed towards minimal mortality in the controls, which is not representative for natural systems where mortality is often high. This methodological bias, generated from assays where mortality in the control group is systematically …

MSU’s earthworm research to aid US study on bio artificial liver

“We can make a breakthrough in the field of regeneration of organs” A research being conducted on the Manonmaniam Sundaranar University (MSU) campus here on the earthworm’s regenerative capacity and its genome has attracted the attention of a researcher from the Department of Regenerative Medicine from Cedars – Sinai, the …

WHO urged to allow experimental drugs in 'dire' Ebola outbreak

Three of the world's leading Ebola specialists called on Tuesday for experimental drugs and vaccines to be offered to people in West Africa, where a vast outbreak of the deadly disease is raging in three countries. Noting that American aid workers who contracted the disease in Liberia were given an …

Incidence and antimicrobial susceptibility of Neisseria gonorrhoeae isolates from patients attending the national Neisseria gonorrhoeae reference laboratory of Hungary

The Hungarian national guidelines for the treatment of gonorrhoea were published in 2002 but are now widely considered to be outdated. Improved knowledge is needed with respect to the epidemiology and antimicrobial susceptibility of Neisseria gonorrhoeae strains currently circulating in Hungary not least for the construction of updated local recommendations …

Protective efficacy and safety of three antimalarial regimens for the prevention of malaria in young Ugandan children: A randomized controlled trial

Chemoprevention offers a promising strategy for prevention of malaria in African children. However, the optimal chemoprevention drug and dosing strategy is unclear in areas of year-round transmission and resistance to many antimalarial drugs. To compare three available regimens, we conducted an open-label randomized controlled trial of chemoprevention in Ugandan children. …

Questions and Answers on experimental treatments and vaccines for Ebola

This FAQ addresses questions the public has about potential treatments and vaccines for Ebola.

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