Micro Organisms

State of the Climate in Asia 2024

The World Meteorological Organization’s State of the Climate in Asia 2024 report warns that the region is warming nearly twice as fast as the global average, driving more extreme weather and posing serious threats to lives, ecosystems, and economies. In 2024, Asia experienced its warmest or second warmest year on …

Food Safety and Standards (Food Products Standards and Food Additives) Second Amendment Regulations, 2022

The Food Safety and Standard Authority of India (FSSAI) on October 27, 2022, published the Food Safety and Standards (Food Products Standards and Food Additives) Second Amendment Regulations, 2022 to further Amend the draft Food Safety and Standards (Food Products Standards and Food Additives) Amendment Regulations, 2021. The Amendments are …

Order of the National Green Tribunal regarding Musi river pollution, Hyderabad, Telangana, 06/12/2019

Order of the National Green Tribunal in the matter of Mohammed Nayeem Pasha & Others Vs The State of Telangana & Others dated 06/12/2019 regarding remedial action against pollution of river Musi at Hyderabad, Telangana which is reported to be contaminated due to industrial and domestic sewage discharged into the …

Antimicrobial movement from agricultural areas to the environment: the missing link - a role for nuclear techniques

Antimicrobials (AM) play a critical role in the treatment of human and animal (aquatic and terrestrial) diseases, which has led to their widespread application and use. Antimicrobial resistance (AMR) is the ability of microorganisms (e.g. bacteria, viruses and some parasites) to stop an antibiotic, such as an antimicrobial, antiviral or …

Order of the Supreme Court regarding disinfection of aircrafts through the process of fumigation, 02/07/2019

Order of the Supreme Court in the matter of Interglobe Aviation Limited Vs Union of India dated 02/07/2019 regarding disinfection of aircrafts through the process of fumigation. Justice D. Y. Chandrachud and Justice Indira Banerjee asks the Union government to consider the feasibility of setting up a high powered committee …

The global threat of antimicrobial resistance and the challenges and needs of Developing Countries

Antimicrobial resistance (AMR) – in which a microorganism (such as a bacterium, virus, fungus or parasite) becomes resistant to an antimicrobial drug used to treat infections caused by it – is possibly the most serious public health threat of our time. Recognising the gravity of the problem, the international community …

Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidence map can support governments in making evidence-informed decisions about implementing programs to …

A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses

Rhino- and enteroviruses are important human pathogens, against which no antivirals are available. The best-studied inhibitors are “capsid binders” that fit in a hydrophobic pocket of the viral capsid. Employing a new class of entero-/rhinovirus inhibitors and by means of cryo–electron microscopy (EM), followed by resistance selection and reverse genetics, …

Development of antiseptic adaptation and cross-adapatation in selected oral pathogens in vitro

There is evidence that pathogenic bacteria can adapt to antiseptics upon repeated exposure. More alarming is the concomitant increase in antibiotic resistance that has been described for some pathogens. Unfortunately, efects of adaptation and cross-adaptation are hardly known for oral pathogens, which are very frequently exposed to antiseptics. Therefore, this …

Vibrio sp. dhg as a platform for the biorefinery of brown macroalgae

Although brown macroalgae holds potential as an alternative feedstock, its utilization by conventional microbial platforms has been limited due to the inability to metabolize one of the principal sugars, alginate. Here, we isolate Vibrio sp. dhg, a fast-growing bacterium that can efficiently assimilate alginate. Based on systematic characterization of the …

Curd-peptide based novel hydrogel inhibits biofilm formation, quorum sensing, swimming mortility of multi-antibiotic resistant clinical isolates and accelerates wound healing activity

The search for a bioactive natural antibacterial agent with wound healing properties is a common practice for the development of new-generation molecules. Antimicrobial peptides are a good alternative to antibiotics and easy-to-form hydrogels under self-assembled conditions without pH adjustment. With this in mind, the peptide pool was extracted from a …

Potential of fungi isolated from the dumping sites mangrove rhizosphere soil to degrade polythene

Polythene is the most widely used plastic around the globe. Among the total plastic waste generated, polythene contributes the maximum share (64%). Various strategies/methods are being utilized to deal with the increasing rate of plastic waste, but among all the methods, bioremediation is regarded as the ecofriendly and widely accepted …

The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype

Skin barrier dysfunction has been reported in both atopic dermatitis (AD) and food allergy (FA). However, only one-third of patients with AD have FA. The purpose of this study was to use a minimally invasive skin tape strip sampling method and a multiomics approach to determine whether children with AD …

Understanding drivers of antibiotic resistance genes in High Arctic soil ecosystems

Soils in tropical and temperate locations are known to be a sink for the genetic potential of anthropogenic-driven acquired antibiotic resistance (AR). In contrast, accumulation of acquired AR is less probable in most Polar soils, providing a platform for characterizing background resistance and establishing a benchmark for assessing AR spread. …

Decomposition of biowaste macronutrients, microbes, and chemicals in black soldier fly larval treatment: A review

Processing of biowaste with larvae of the black soldier fly, Hermetia illucens L. (Diptera: Stratiomyidae), is an emerging waste treatment technology. Larvae grown on biowaste can be a relevant raw material for animal feed production and can therefore provide revenues for financially viable waste management systems. In addition, when produced …

Identification of risk factors associated with carriage of resistant Escherichia coli in three culturally diverse ethnic groups in Tanzania: a biological and socioeconomic analysis

Improved antimicrobial stewardship, sanitation, and hygiene are WHO-inspired priorities for restriction of the spread of antimicrobial resistance. Prioritisation among these objectives is essential, particularly in low-income and middle-income countries, but the factors contributing most to antimicrobial resistance are typically unknown and could vary substantially between and within countries. We aimed …

Pollution and environmental stressors modulate the microbiome in estuarine mangroves: a metagenome analysis

The microbial communities of mangroves which form important links in elemental cycling and bioremediation have not been elucidated in most parts of the world. Due to urbanization and deforestation mangroves are also under threat. In the present study, high throughput next generation sequencing technology, based on 16S rRNA amplicon analysis …

Introduction and geographic availability of new antibiotics approved between 1999 and 2014

Despite the urgent need for new, effective antibiotics, few antibiotics of value have entered the market during the past decades. Therefore, incentives have been developed to stimulate antibiotic R&D. For these incentives to be effective, geographic availability for recently approved antibiotics needs to be better understood. In this study, we …

Preserving microbial diversity

Microbiota from humans of all cultures are needed to ensure the health of future generations. Original Source

Personalized gut mucosal colonization resistance to empiric probiotics is associated with unique host and microbiome features

Empiric probiotics are commonly consumed by healthy individuals as means of life quality improvement and disease prevention. However, evidence of probiotic gut mucosal colonization efficacy remains sparse and controversial. We metagenomically characterized the murine and human mucosal-associated gastrointestinal microbiome and found it to only partially correlate with stool microbiome. A …

Anthropological and socioeconomic factors contributing to global antimicrobial resistance: a univariate and multivariable analysis

Understanding of the factors driving global antimicrobial resistance is limited. We analysed antimicrobial resistance and antibiotic consumption worldwide versus many potential contributing factors. Original Source

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