Drugs

Order of the Supreme Court regarding ART drugs for people living with HIV/AIDS, 24/02/2025

Order of the Supreme Court of India in the matter of Network of People Living With HIV/AIDS & Others Vs Union of India & Others dated 24/02/2025. The Supreme Court (SC), February 24, 2025 has directed all states to file their affidavits addressing concerns raised about antiretroviral therapy (ART) drugs …

Health ministry mulled compulsory licencing of rare disease drugs

NEW DELHI: The health ministry was actively mulling compulsory licensing, apart from price capping, of “orphan drugs” (for rare diseases), when the department of pharmaceuticals abruptly issued an order exempting such medicines from price control, derailing plans to make these drugs affordable. The health ministry discussed price capping and invoking …

President orders plan to alleviate poverty

President Maithripala Sirisena has ordered officials to prepare a plan in the new year to alleviate poverty in the country. Addressing public officials at the Polonnaruwa District Secretariat, the President emphasised the need to eliminate the drug menace and bolster projects that were already underway to tackle the drug menace. …

Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009–15

Antimicrobial resistance (AMR) is a priority for surveillance in bacterial infections. For leprosy, AMR has not been assessed because Mycobacterium leprae does not grow in vitro. We aim to obtain AMR data using molecular detection of resistance genes and to conduct a prospective open survey of resistance to antileprosy drugs …

DR Congo begins first-ever multi-drug Ebola trial

The Ministry of Health of the Democratic Republic of the Congo (DRC) today announced that a randomized control trial has begun to evaluate the effectiveness and safety of drugs used in the treatment of Ebola patients. The trial is the first-ever multi drug trial for an Ebola treatment. It will …

Top drugmakers not doing enough to provide medicines to poor countries: Report

Many of the world's top drugmakers are not doing enough to provide medicines to poor countries, leaving big gaps in access to treatments in crucial disease areas, including cancer, according to a new report on Tuesday. The non-profit Access to Medicine Foundation (AMF) found companies overall were doing more than …

Clinical trial of injectable ARV drug starts in Uganda

Uganda has started recruiting women for trials of a long-lasting injectable antiretroviral drug for Pre-Exposure Prophylaxis. This is part of a large scale trial that will also be conducted in six other countries — Kenya, Malawi, Botswana, Zimbabwe, South Africa and Swaziland. A total of 3,200 individuals are expected to …

Access to medicine index 2018

The Access to Medicine Index finds that a handful of pharmaceutical companies are developing the bulk of urgently needed new medicines for the poor. The development of new medical products that are considered the highest priority for people in developing countries is highly concentrated - among five pharmaceutical companies and …

Introduction and geographic availability of new antibiotics approved between 1999 and 2014

Despite the urgent need for new, effective antibiotics, few antibiotics of value have entered the market during the past decades. Therefore, incentives have been developed to stimulate antibiotic R&D. For these incentives to be effective, geographic availability for recently approved antibiotics needs to be better understood. In this study, we …

Order of the Supreme Court of India regarding Drug Price Control Order 2013, 10/10/2018

Order of the Supreme Court of India in the matter of All India Drug Action Network & Others Vs Union of India & Others dated 10/10/2018 regarding Drug Price Control Order 2013. Counsel for the All India Drug Action Network in 2015 had confined his submission to four major issues …

Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 …

The morbidity and socioeconomic effects of onchocerciasis, a parasitic disease that is primarily endemic in sub-Saharan Africa, have motivated large morbidity and transmission control programmes. Annual communitydirected ivermectin treatment has substantially reduced prevalence. Elimination requires intensified efforts, including more efficacious treatments. We compared parasitological efficacy and safety of moxidectin and …

Global tuberculosis report 2018

India accounted for 27 per cent of the 10 million people who developed tuberculosis in 2017, the highest among the top 30 high TB burden countries in the world, according to this WHO report The 2018 edition of the Global Tuberculosis Report, provides a comprehensive and up-to-date assessment of the …

Judgement of the Supreme Court of India regarding leprosy eradication in India, 14/09/2018

Judgement of the Supreme Court of India in the matter of Pankaj Sinha Vs Union of India & Others dated 14/09/2018 regarding determination of new cases of leprosy and to publish and bring in the public domain the reports of National Sample Survey on Leprosy conducted in 2010-2011 and further …

Order of the Supreme Court of India regarding the Draft Drugs and Clinical Trials Rules 2018, 12/09/2018

Order of the Supreme Court of India in the matter of Swasthya Adhikar Manch & Others Vs Union of India & Others dated 12/09/2018 regarding Draft Drugs and Clinical Trials Rules 2018. The Government of India has issued Drugs and Clinical Trials Rules, 2018 in February, 2018. The Draft Rules …

Anthropological and socioeconomic factors contributing to global antimicrobial resistance: a univariate and multivariable analysis

Understanding of the factors driving global antimicrobial resistance is limited. We analysed antimicrobial resistance and antibiotic consumption worldwide versus many potential contributing factors. Original Source

DRC approves Ebola drugs as death toll rises to 61

The Ebola death toll has risen to 61 in the Democratic Republic of Congo, where health officials are working to contain the outbreak in the North Kivu and Ituri provinces. Most of the fatalities have been in Mabalako, where 50 people have died. Another three fatal cases are reported in …

New HIV therapy can boost immunity

Turns out, a new HIV drug can reduce the viral replication and increase immune cells in individuals with advanced, drug-resistant HIV infection. Used in combination with existing HIV medications, the drug is a promising strategy for patients who have run out of effective treatment options, the researchers at Yale University …

State Council: guilty producers to be severely punished, officials held accountable for substandard vaccines

Decisions were made at the State Council's executive meeting chaired by Premier Li Keqiang Thursday, following a report on the findings of investigations into the case of substandard vaccine producer of Changchun Changsheng Life Sciences Ltd.. Mandated by the Communist Party of China Central Committee and the State Council, the …

Study reveals fake medicines are rife in Africa

In Southern Africa‚ Malawi has the most medicines commonly sold in substandard or falsified condition‚ according to pharmacists from the University of North Carolina. SA’s problem is relatively small‚ they reported on Friday in the journal JAMA Network Open‚ after analysing 96 previous studies of falsified and substandard medicines in …

Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways

Drugs that are already clinically approved or experimentally tested for conditions other than cancer, but are found to possess previously unrecognized cytotoxicity towards malignant cells, may serve as ftting anti-cancer candidates. Methyl N-(6-phenylsulfanyl-1H benzimidazol-2-yl) carbamate [Fenbendazole, FZ], a benzimidazole compound, is a safe and inexpensive anthelmintic drug possessing an efcient …

Anti-bodies that fight Ebola viruses are now a reality

Finally, anti-bodies to three major Ebola viruses have now been developed. Researchers at Vanderbilt University Medical Center are a step closer to developing a broadly effective antibody treatment against these viruses that cause the lethal disease in humans. Researchers found that the isolation of two potent monoclonal antibodies from human …

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