Antimicrobial resistance (AMR) is now recognized as a major global public health problem which has been aggravated by the irrational use of antimicrobial agents in human and animal health as well as the presence of these agents in the environment. AMR in animal pathogens makes disease treatments ineffective, increases the …
Resistance to drugs is a global threat The 28th South Zone conference of the Indian Academy of Paediatrics and the 43rd meet of its Kerala chapter, held here recently, urged the government to formulate an antibiotic policy. The events observed that antibiotic resistance was a global threat and increasingly making …
The evolution of resistance to antimicrobial chemotherapy is a major and growing cause of human mortality and morbidity. Comparatively little attention has been paid to how different patient treatment strategies shape the evolution of resistance. In particular, it is not clear whether treating individual patients aggressively with high drug dosages …
Antibiotics are emerging environmental contaminants, causing both short-term and long-term alterations of natural microbial communities due to their high biological activities. The antibiotic resistance pattern of bacteria from anthropogenic polluted Oluwa River, Nigeria was carried out. Microbial profiling and antibiotic sensitivity tests were carried out on water and sediment samples …
Poultry farmers can now afford to count their profits before their chickens hatch -and they are big, weighing on average twice as much as they did 50 years ago.The broiler chicken of today ,a product of controlled breeding, weighs around 2.2kg as compared to 1.2kg before 1960, say veterinarians and …
Neonatal mortality—death that occurs during the first 28 days of life—accounts for nearly half of all the deaths that occur in children before they reach their fifth birthday. Worldwide, nearly 3 million neonatal deaths occur every year. Three bacterial infections—sepsis (infection of the bloodstream), pneumonia (infection of the lungs), and …
Livestock operations are known to harbor elevated levels of antibiotic resistance genes (ARGs) that may pose a threat to public health. Broiler feedlots may represent an important source of ARGs in the environment. However, the prevalence and dissemination mechanisms of various types of ARGs in the environment of broiler feedlots …
The objective of the study was to estimate the impact on maternal and child mortality after eliminating user fees for pregnant women and for children less than five years of age in Burkina Faso.
Obesity is recognized as a major public health problem in recent times. One out of every 5 children in the U.S. is known to be overweight or obese and this number continues to rise. This excess of body fat negatively affects the child's health and wellbeing. The World Health Organization …
The governor of California on Tuesday vetoed a first-in-the-nation state law to reduce the use of antibiotics in livestock production and said lawmakers should look for “new and effective ways” to prevent antibiotic overuse. The bill would have outlawed the use of antibiotics for growth in animals and required all …
Young children who are given repeated courses of antibiotics are at greater risk than those who use fewer drugs of becoming obese, US researchers say. The JAMA Pediatrics report found children who had had four or more courses by the age of two were at a 10% higher risk of …
Patna: Antibiotics consumption in Bihar has increased from 12% in 2009 to 20% today. According to state drug control department, Biharis consume antibiotics worth over Rs 600 crore every year. On the Rational Antibiotic Day on Sunday, doctors said the 'abuse' of antibiotics has led not only to side effects …
Scientists have designed a new class of antibiotic which seeks and destroys resistance genes in bacteria. The unique approach could be used to genetically engineer bacteria in our bodies to become less dangerous. The technology might also lead to new treatments for metabolic diseases like obesity, the researchers claim. Scientists …
Repeated exposure of the bacterium Escherichia coli to clinically relevant concentrations of ampicillin results in the evolution of tolerance—the ability to survive until the antibiotic concentration diminishes—through an extension of the lag phase, a finding that has implications for slowing the evolution of antibiotic resistance.
While small molecule inhibitors of the bacterial ribosome have been instrumental in understanding protein translation, no such probes exist to study ribosome biogenesis. We screened a diverse chemical collection that included previously approved drugs for compounds that induced cold sensitive growth inhibition in the model bacterium Escherichia coli. Among the …
Only about 10 percent of the antibiotics used in chicken are actually used in humans, says the National Chicken Council. Its statement comes on the heels of a controversial report by Reuters indicating increasing proof that the prophylactic medications used in chickens are fueling antibiotic resistance not just in fowl, …
Kathleen Holloway and David Henry evaluate whether countries that report having implemented WHO essential medicines policies have higher quality use of medicines.
“Microorganisms are the best chemists on the planet,” declared Michael A. Fischbach, a chemist at the University of California, San Francisco. For evidence, Fischbach points to the many lifesaving drugs that microorganisms produce. In 1928, for example, Alexander Fleming discovered that mould wafting into his lab produced a bacteria-killing chemical …
Groundwater pollution due to anthropogenic activities may impact overall groundwater quality. Organic and inorganic pollutants have been routinely detected at unsafe levels in groundwater rendering this important drinking water resource practically unusable. Vulnerability of groundwater pollution and subsequent impact has been documented in various studies across the globe. Field studies …
This is the first recorded presence of this particular strain of deadly antibiotic resistant ‘super bug’ in India A deadly bacteria variant known as NDM-4, which is also called the “super bug”, has been found by the medical researchers at Jawaharlal Nehru Medical College of Aligarh Muslim University from the …
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) was recognized in Europe and worldwide in the late 1990s. Within a decade, several genetically and geographically distinct CA-MRSA lineages carrying the small SCCmec type IV and V genetic elements and the Panton-Valentine leukocidin (PVL) emerged around the world. In Europe, the predominant CA-MRSA strain …
