Antimicrobial resistance (AMR) is now recognized as a major global public health problem which has been aggravated by the irrational use of antimicrobial agents in human and animal health as well as the presence of these agents in the environment. AMR in animal pathogens makes disease treatments ineffective, increases the …
GENEVA - The World Health Organization published a new classification of antibiotics Tuesday that aims to fight drug resistance, with penicillin-type drugs recommended as the first line of defense and others for use only when absolutely necessary. The new 'essential medicines list' includes 39 antibiotics for 21 common syndromes, categorized …
The mobile colistin resistance gene mcr-1 has attracted global attention, as it heralds the breach of polymyxins, one of the last-resort antibiotics for the treatment of severe clinical infections caused by multidrug-resistant Gram-negative bacteria. To date, six slightly different variants of mcr-1, and a second mobile colistin resistance gene, mcr-2, …
High antibiotic and antifungal concentrations in wastewater from anti-infective drug production may exert selection pressure for multidrug-resistant (MDR) pathogens. We investigated the environmental presence of active pharmaceutical ingredients and their association with MDR Gram-negative bacteria in Hyderabad, South India, a major production area for the global bulk drug market. Original …
The Centre's recent move to come out with an action plan to tackle Antimicrobial Resistance (AMR) is a "big" step to increase inter-agency cooperation to tackle the public health challenge, a green body said today. Around 11 ministries, including health, environment, agriculture and food and public distribution, had yesterday adopted …
Antimicrobial resistance is a serious threat to global public health that requires action across all government sectors and society and is driven by many interconnected factors. Single, isolated interventions have limited impact and coordinated action is required to minimize the emergence and spread of antimicrobial resistance. This was stated by …
Antibiotic-resistant bacteria are an escalating grim menace to global public health. Our aim is to phenotype and genotype antibiotic-resistant commensal Escherichia coli (E. coli) from humans, animals, and water from the same community with a ‘one-health’ approach. Original Source
Gut microbiomes play crucial roles in animal health, and shifts in the gut microbial community structure can have detrimental impacts on hosts. Studies with vertebrate models and human subjects suggest that antibiotic treatments greatly perturb the native gut community, thereby facilitating proliferation of pathogens. In fact, persistent infections following antibiotic …
MUMBAI: Five years after the emergence of totally drug-resistant tuberculosis bacteria in India, the World Health Organisation (WHO) on Monday published its first-ever list of antibiotic-resistant "priority pathogens" - a catalogue of 12 families of bacteria that pose the greatest threat to human health. Antibiotic resistant or antimicrobial resistance has …
The Food Safety and Standards Authority of India (FSSAI) had issued a notice in November 2015, calling for claims, suggestions, views, comments etc. from stakeholders on the draft amendment related to pharmacologically active substance prohibited for fish and fishery products; harmonization of insecticides, antibiotics and veterinary drugs residues; and fixation …
They say instead of focussing on antibiotics, it has to explore other alternatives At a time when India is battling a crisis of antibiotic resistance and a few drugs in the pipeline, the government’s plan to eradicate tuberculosis by 2025 seems an unachievable target, say doctors. The mention of TB …
In the wake of the recent death of an American woman after contracting an infection resistant to antibiotics, the drug regulator has directed the pharma supply chain, including retailers, chemists and drug makers, to strictly follow norms while selling antibiotics. The Drugs Controller General of India (DCGI) has also asked …
Tirupati: A team of researchers from Israel is now working on finding a genetic solution to the ever-increasing menace of antibiotic resistance to a plethora of diseases including tuberculosis (TB) and hospital-acquired infections. The team has targeted the notorious bacteria called methicillin-resistant Staphylococcus aureus (MRSA). This bacteria is quite common …
The objective of the study is to describe the frequency and factors associated with antibiotic use in early childhood, and estimate the proportion of diarrhoea and respiratory illnesses episodes treated with antibiotics. Original Source
The Strategic and Operational Guidance presented in this document is based on expert inputs and deliberations held at the International Workshop on National Action Plan on Antimicrobial Resistance for Developing Countries. The workshop, focusing on animal and environmental aspects, was organized by the Centre for Science and Environment (CSE) on …
Antibiotic-resistant bacterial infections are on the rise and pose a serious threat to society. The influence of genetic resistance mechanisms on antibiotic therapy is well described. However, other factors, such as epigenetic resistance or the impact of the environment on antibiotic therapy, are less well understood. Here, we describe and …
MUMBAI: India's commerce ministry has hit back at reports by environmental lobby groups which have blamed the production methods of Indian drug companies as one of the main reasons for the rise of super bugs, or drug resistant bacteria. The Pharmaceuticals Export Council of India (Pharmexcil) set up by the …
With possible far-reaching consequences for the pharmaceutical industry in India, a report from a European agency campaigning for the environment has blamed manufactures in Hyderabad for growing antibiotic resistance in the world. Titled ‘Superbugs in the Supply Chain’, the report by London-based Changing Markets Foundation aims to show how effluents …
The objective of the study was to evaluate the association between the income status of a country and the prevalence of antimicrobial resistance (AMR) in the three most common bacteria causing infections in hospitals and in the community: third-generation cephalosporin (3GC)-resistant Escherichia coli, methicillin-resistant Staphylococcus aureus (MRSA), and 3GC-resistant Klebsiella …
The Centre for Science and Environment (CSE) in 2014 highlighted the rampant use of antibiotics in the poultry sector and presence of antibiotic residues in chicken meat. Earlier, in 2010, CSE had also found similar antibiotic-use practices in bees for honey. We now travelled across several districts of West Bengal—a …
Antimicrobial resistance (AMR) arises when microorganisms such as bacteria survive exposure to a drug that would normally kill them or stop their growth. AMR is globally recognized as an emerging public health threat as antibiotics are becoming increasingly ineffective against disease-causing bacteria. AMR is linked with greater spread of infectious …
