The Ministry of New and Renewable Energy has published the R&D; Roadmap for Green Hydrogen Ecosystem in India. This document was published on 13th October, 2023. One of the central pillars of the National Green Hydrogen Mission is the establishment of a supportive research and innovation ecosystem for green hydrogen …
Black patients have higher lung cancer risk despite lower pack years of smoking. The researchers assessed lung cancer risk by race, ethnicity, and sex among a nationally representative population eligible for lung cancer screening based on Medicare criteria. Original Source
A furious debate that is raging in Brazil pits the nation’s largest university against hundreds of cancer patients who want access to a compound that some have branded a miracle cure. (Editorial) Original Source
Malaria continues to impose enormous health and economic burdens on the developing world. Novel technologies proposed to reduce the impact of the disease include the introgression of parasite-resistance genes into mosquito populations, thereby modifying the ability of the vector to transmit the pathogens. Such genes have been developed for the …
The tumor microenvironment plays in an important role in the progression of cancer by mediating stromal-epithelial paracrine signaling, which can aberrantly modulate cellular proliferation and tumorigenesis. Exposure to environmental toxicants, such as inorganic arsenic (iAs), has also been implicated in the progression of prostate cancer. Original Source
Future of Energy is one of the most significant challenge mankind faces today. Despite this challenge, if you randomly pick ten science students, chances are that nine of them would have heard about CERN, the Swiss particle accelerator, but may be none would have heard about ITER, the largest international …
Cell-cycle progression and cell division in eukaryotes are governed in part by the cyclin family and their regulation of cyclin-dependent kinases (CDKs). Cyclins are very well characterised in model systems such as yeast and human cells, but surprisingly little is known about their number and role in Plasmodium, the unicellular …
The objective of the study was to identify mechanisms for cancer resistance in elephants and compare cellular response to DNA damage among elephants, healthy human controls, and cancer-prone patients with Li-Fraumeni syndrome (LFS).
The objective of the study was to examine the cross-sectional relationships between standing time, obesity, and metabolic syndrome alongside and independent of leisure-time physical activity (LTPA).
Global environmental change necessitates increased predictive capacity; for forests, recent advances in technology provide the response to this challenge. “Next-generation” remote-sensing instruments can measure forest biogeochemistry and structural change, and individual-based models can predict the fates of vast numbers of simulated trees, all growing and competing according to their ecological …
Researchers hope to show that using the gas as a raw material could make an impact on climate change. On 29 September, the XPRIZE Foundation based in Culver City, California, announced a 4½-year competition that will award US$20 million to the research team that can come up with the best …
This is the twentieth global report on tuberculosis (TB) published by WHO in a series that started in 1997. It provides a comprehensive and up-to-date assessment of the TB epidemic and progress in implementing and financing TB prevention, care, control and research at global, regional and country levels using data …
The past was a world of giants, with abundant whales in the sea and large animals roaming the land. However, that world came to an end following massive late-Quaternary megafauna extinctions on land and widespread population reductions in great whale populations over the past few centuries. These losses are likely …
In October, 2015, 22 scientists from ten countries met at the International Agency for Research on Cancer (IARC) in Lyon, France, to evaluate the carcinogenicity of the consumption of red meat and processed meat. The Working Group assessed more than 800 epidemiological studies that investigated the association of cancer with …
Artemisinin-resistant Plasmodium falciparum parasites are rapidly spreading in Southeast Asia, yet nothing is known about their transmission. This knowledge gap and the possibility that these parasites will spread to Africa endanger global efforts to eliminate malaria. Here we produce gametocytes from parasite clinical isolates that displayed artemisinin resistance in patients …
Antigens encoded by the var gene family are major virulence factors of the human malaria parasite Plasmodium falciparum, exhibiting enormous intra- and interstrain diversity. Here we use network analysis to show that var architecture and mosaicism are conserved at multiple levels across the Laverania subgenus, based on var-like sequences from …
The high prevalence of sickle haemoglobin in Africa shows that malaria has been a major force for human evolutionary selection, but surprisingly few other polymorphisms have been proven to confer resistance to malaria in large epidemiological studies. To address this problem, we conducted a multi-centre genome-wide association study (GWAS) of …
MB-003, a plant-derived monoclonal antibody cocktail used effectively in treatment of Ebola virus infection in non-human primates, was unable to protect two of six animals when initiated 1 or 2 days post-infection. We characterized a mechanism of viral escape in one of the animals, after observation of two clusters of …
Ashlee Earl and colleagues use whole genome sequencing and dating analysis of TB isolates from KwaZulu-Natal to identify when the mutations that confer extensive drug resistance evolved. Original Source
Thioester-containing protein 1 (TEP1) is a key immune factor that determines mosquito resistance to a wide range of pathogens, including malaria parasites. Here we report a new allele-specific function of TEP1 in male fertility. Original Source
Obesity is involved in several cardiovascular diseases including coronary artery disease and endothelial dysfunction. Endothelial Endothelium vasodilator and vasoconstrictor agonists play a key role in regulation of vascular tone. In this study, we evaluated coronary vascular response in an 8 weeks diet-induced obese C57BL/6 mice model. Coronary perfusion pressure in …
