Drugs

Order of the Supreme Court regarding ART drugs for people living with HIV/AIDS, 24/02/2025

Order of the Supreme Court of India in the matter of Network of People Living With HIV/AIDS & Others Vs Union of India & Others dated 24/02/2025. The Supreme Court (SC), February 24, 2025 has directed all states to file their affidavits addressing concerns raised about antiretroviral therapy (ART) drugs …

Chemical genetics of Plasmodium falciparum

Malaria caused by Plasmodium falciparum is a disease that is responsible for 880,000 deaths per year worldwide. Vaccine development has proved difficult and resistance has emerged for most antimalarial drugs. To discover new antimalarial chemotypes, we have used a phenotypic forward chemical genetic approach to assay 309,474 chemicals. Here we …

Thousands of chemical starting points for antimalarial lead identification

There are still nearly 250 million malaria cases reported annually, over 800,000 fatal, with most deaths being children under 5. The malaria parasite Plasmodium falciparum is notoriously adept at developing drug resistance, and new drugs are urgently needed. Two reports raise hopes that alternatives to artemisinins might be found, by …

Priming the antimalarial pipeline

There are still nearly 250 million malaria cases reported annually, over 800,000 fatal, with most deaths being children under 5. The malaria parasite Plasmodium falciparum is notoriously adept at developing drug resistance, and new drugs are urgently needed. Two reports raise hopes that alternatives to artemisinins might be found, by …

Neglected diseases fund touted

Despite decades of research into drugs and vaccines for neglected diseases such as tuberculosis and dengue fever, few products have made it through clinical development and into the hands of the millions who desperately need them. One of the biggest hurdles is the sheer expense of running clinical trials, compared …

Change of purpose

In 2007, a paper in the journal Cancer Cell announced that the compound dichloroacetate (DCA) had been found to shrink tumours in rats (S. Bonnet et al. Cancer Cell 11, 37

Zydus gets DCGI nod for swine flu vaccine

INDIA will finally get its own vaccine for the dreaded swine flu, two months after the government granted approval to French drug major Sanofi Pasteur SA for inoculation of frontline health workers and individuals under high risk of contracting the virus. Ahmedabad-based Zydus Cadila has received the approval from the …

Glenmark, Merck reach truce in cholesterol drug patent dispute

Investors Put Off By 2016 Launch Date Given To Glenmark, Stock Sheds 1.7% GLENMARK Pharmaceuticals and US drugmaker Merck & Co have settled out of court their patent dispute over cholesterol control drug ezetimibe but investors were unimpressed with the terms of the deal, sending the company

Govt to approach WTO on EU drug seizure

After clarifying miscommunications with their Brazilian counterparts, the commerce ministry is on the verge of filing a suit against the European Union for their seizure of generic pharmaceutical drugs headed for the South American nation. Following recent dialogue with Brasilia and after evaluating the EU

Govt hospitals to prescribe generic drugs

In a move that will help bring down healthcare costs, the Union Health Ministry has directed central government-run hospitals to prescribe only generic drugs from now on.

Tide turns for drug manufacturing in Africa

With several efforts underway to increase the local production of drugs in developing countries, Tatum Anderson assesses the pros and cons of manufacturing medicines in Africa.

No time to wait

A pioneering open source effort on development of new drugs promises to breathe new life into treatment of TB. (Editorial)

Patent office strips Roche of rights over Valcyte

Our Bureau NEW DELHI SWISS drugmaker Roche lost the patent in India for its anti-viral drug, Valcyte, widely used by AIDS patients, after the patent office concluded it did not contain the necessary innovation to qualify for marketing exclusivity, said lawyers involved in the case. The ruling would help local …

EU assures FTA wont lead to costlier life-saving drugs

THE European Commission has said the proposed free trade agreement (FTA) negotiations with India will not affect production of cheap life-saving medicines in the country.

Drugs in the environment: Do pharmaceutical take-back programs make a difference?

The state of Maine experimented with drugs last year. The state had already tested several methods?for collecting unused pharmaceuticals, with varying degrees of success. After tracking surprisingly high concentrations of pharmaceuticals in landfill leachate

Banana and its by-product utilisation: an overview

Banana serves as an ideal and low cost food source for developing countries where most of the population rely mostly on bananas for food. Banana plant parts are useful as insecticide, antioxidant, colour absorber, in preparation of various functional foods, wine, alcohol, biogas, cattle feed etc. This review discusses usefulness …

Revealed: Pfizer's payments to censured doctors

The drug company paid experts disciplined for deficiencies in patient care to lecture other doctors on prescribing, finds an analysis by New Scientist.

Pfizer's payments to censured doctors

They are billed as "healthcare professionals who spend years building expertise in their fields". Using materials grounded in science, they educate their peers in the risks and benefits of drugs. This is how Pfizer, the pharmaceuticals giant, describes the experts it hires to lead forums in which doctors are lectured …

Finmin says no to dumping duty on pharma ingredients

Fear That Prices Of Some Antibiotics Could Flare Up Prompts Ministry To Take Unusual Move THE finance ministry has shot down an anti-dumping duty proposed by a key government body on import of certain drug inputs from China and Mexico for fear that prices of some popular antibiotics could flare …

The thalidomide story explained

TAWANA WILLIAMS types, eats and braids hair with her feet. She does not have a choice. She entered the world without arms. Williams, born in Wilson, USA, was one of the 12, 000 babies around the world who either died or were born with severe limb defects in the early …

Kills more than the pain

IMAGINE pain without painkillers around. Aspirin was the first such drug synthesized by Carl von Gerhardt in 1853. The name was patented by Bayer Company in 1899. John Vane was awarded the Nobel Prize in 1982 for explaining its mechanism. “A doctor prescribes painkillers and anti-inflammatory drugs as the first …

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