Diagnostic Methods

Order of the National Green Tribunal regarding dumping yard at Baliapanda, Puri district, Odisha, 24/03/2025

Order of the National Green Tribunal (Eastern Zone Bench, Kolkata) in the matter of Haripriya Patel Vs State of Odisha & Others dated 24/03/2025. The matter related to the dumping yard at Baliapanda which is situated 50-100 meter away from Puri sea beach and a few km away from Puri …

The tuberculosis cascade of care in India’s public sector: A systematic review and meta-analysis

India has 23% of the global burden of active tuberculosis (TB) patients and 27% of the world’s “missing” patients, which includes those who may not have received effective TB care and could potentially spread TB to others. The “cascade of care” is a useful model for visualizing deficiencies in case …

Enhanced surveillance for fatal dengue-like acute febrile illness in Puerto Rico, 2010-2012

Dengue is a major public health problem in the tropics. Despite its global importance, population-based mortality rates attributable to dengue are largely unknown. Dengue vaccines are now in late stage clinical trials and one vaccine has been licensed in several countries. Evidence-based decisions regarding the future use of dengue vaccines …

Global trends and predictions in ovarian cancer mortality

Over the last two decades, ovarian cancer mortality rates have levelled or declined. There are, however, persisting and substantial differences in ovarian cancer patterns and trends. Researchers updated global trends in ovarian cancer mortality to 2012, and predicted trends in rates to 2020 using data from the World Health Organization …

Detecting Guillain-Barré syndrome caused by Zika virus using systems developed for polio surveillance

Zika virus disease is caused by a ribonucleic acid (RNA) virus, which is transmitted to humans by mosquitoes of the Aedes aegypti species. Around 80% of infections are asymptomatic. Symptomatic infections are characterized by mild fever lasting from four to seven days, associated with maculopapular rash, arthralgia, conjunctivitis, muscle pain …

Expanded Indian National Rotavirus Surveillance Network in the context of Rotavirus Vaccine introduction

The objective of the study was to extend a nation-wide rotavirus surveillance network in India, and to generate geographically representative data on rotaviral disease burden and prevalent strains. Original Source

The patient with multiple mesenteric cystic lymhangioma was treated in neonatal perıod through prenatal diagnosis: Case report and literature review

Mesenteric cystic lymphangiomas are benign congenital tumors characterized by the proliferation of lymphatic channels. There is an uncommon disorder that constitutes 0.5 % of all lymphangiomas and can cause fatal complications such as volvulus, intestinal obstruction and traumatic or spontaneous rupture, requiring emergency surgery. For this reason, prenatal diagnosis is …

Rare diseases need our attention

A large number of diseases have been grouped together as ‘rare diseases’, because we do not know much about them. There is no consensus on the definition of a rare disease. This is because, obtaining reliable statistical estimates of the frequency of occurrence of a rare event, such as prevalence …

South Africa's bid to end AIDS

South Africa has more people living with HIV, an estimated 6.6 million, than any country in the world. About half are now receiving antiretroviral (ARV) treatment, which has greatly stressed the country's health care system. Now, South Africa plans to encourage all infected people to learn their status and start …

Assessment of schoolchildren for congenital heart disease using murmurs and blood pressure as markers

Congenital heart disease (CHD) is one of the major causes of cardiovascular diseases in developing countries. CHD among neonates and young children is responsible for the largest proportion of mortality (30–50%) caused by birth defects . Though there is a significantly reducing trend observed in both overall and infant mortality …

Zika virus and health systems in Brazil: From unknown to a menace

The unfolding story of Zika virus in the Americas is much more than a mosquito-borne disease that may affect fetal development. It is the story of a disease that exposed problems and raised challenges that the affected health systems and governments cannot ignore. Next, based largely on lessons provided by …

A novel xenomonitoring technique using mosquito excreta/feces for the detection of filarial parasites and malaria

Given the continued successes of the world’s lymphatic filariasis (LF) elimination programs and the growing successes of many malaria elimination efforts, the necessity of low cost tools and methodologies applicable to long-term disease surveillance is greater than ever before. As many countries reach the end of their LF mass drug …

Detecting presymptomatic infection is necessary to forecast major epidemics in the earliest stages of infectious disease outbreaks

We assess how presymptomatic infection affects predictability of infectious disease epidemics. We focus on whether or not a major outbreak (i.e. an epidemic that will go on to infect a large number of individuals) can be predicted reliably soon after initial cases of disease have appeared within a population. For …

Co-distribution and co-infection of chikungunya and dengue viruses

Chikungunya and dengue infections are spatio-temporally related. The current review aims to determine the geographic limits of chikungunya, dengue and the principal mosquito vectors for both viruses and to synthesise current epidemiological understanding of their co-distribution. Three biomedical databases (PubMed, Scopus and Web of Science) were searched from their inception …

Comparative evaluation of validity and cost-benefit analysis of rapid diagnostic test (RDT) kits in diagnosis of dengue infection using composite reference criteria: A cross-sectional study …

Rapid diagnostic test (RDT) kits are widely used in India for the diagnosis of dengue infection. It is important to evaluate the validity and reliability of these RDTs. The study was aimed to determine the sensitivity, specificity and predictive value of four commercially available RDTs [Panbio Dengue Duo cassette, Standard …

An assessment of GLOBOCAN methods for deriving national estimates of cancer incidence

The objective of the study was to assess the validity of the GLOBOCAN methods for deriving national estimates of cancer incidence. The researchers obtained incidence and mortality data from Norway by region, year of diagnosis, cancer site, sex and 5-year age group for the period 1983–2012 from the NORDCAN database. …

Burden of systolic and diastolic left ventricular dysfunction among Hispanics in the United States

Participants of Hispanic/Latino origin across the United States aged 45 to 74 years were enrolled into the Echocardiographic Study of Latinos (ECHO-SOL) and underwent a comprehensive echocardiography examination to define left ventricular systolic dysfunction (LVSD) and left ventricular diastolic dysfunction (LVDD). Clinical HF was defined according to self-report, and those …

Assessment of point-of-care diagnostics for G6PD deficiency in malaria endemic rural eastern Indonesia

Patients infected by Plasmodium vivax or Plasmodium ovale suffer repeated clinical attacks without primaquine therapy against latent stages in liver. Primaquine causes seriously threatening acute hemolytic anemia in patients having inherited glucose-6-phosphate dehydrogenase (G6PD) deficiency. Access to safe primaquine therapy hinges upon the ability to confirm G6PD normal status. CareStart …

A seroepidemiological study of Serogroup A Meningococcal infection in the African Meningitis Belt

The pattern of epidemic meningococcal disease in the African meningitis belt may be influenced by the background level of population immunity but this has been measured infrequently. A standardised enzyme-linked immunosorbent assay (ELISA) for measuring meningococcal serogroup A IgG antibodies was established at five centres within the meningitis belt. Antibody …

Leprosy diagnostic test development as a prerequisite towards elimination: Requirements from the user’s perspective

Leprosy is the complex disease manifestation of Mycobacterium leprae infection. Although prevalence has declined from 5.2 million globally in the 1980s, new annual case detection rates (CDRs) remain high, at more than 200,000 new cases per year, indicating that additional leprosy control strategies are required to halt transmission. Original Source

Nanopore sequencing as a rapidly deployable Ebola outbreak tool

Rapid sequencing of RNA/DNA from pathogen samples obtained during disease outbreaks provides critical scientific and public health information. However, challenges exist for exporting samples to laboratories or establishing conventional sequencers in remote outbreak regions. We successfully used a novel, pocket-sized nanopore sequencer at a field diagnostic laboratory in Liberia during …

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. ...
  8. 16

IEP child categories loading...