Cervix / Uterine Cancer

The burden of cancers and their variations across the states of India: the Global Burden of Disease Study 1990–2016

Previous efforts to report estimates of cancer incidence and mortality in India and its different parts include the National Cancer Registry Programme Reports, Sample Registration System cause of death findings, Cancer Incidence in Five Continents Series, and GLOBOCAN. We present a comprehensive picture of the patterns and time trends of …

Effectiveness of cervical screening after age 60 years according to screening history: Nationwide cohort study in Sweden

The relatively high incidence of cervical cancer in women at older ages is a continuing concern in countries with long-established cervical screening. Controversy remains on when and how to cease screening. Existing population-based studies on the effectiveness of cervical screening at older ages have not considered women’s screening history. We …

Cervical cancer stem cells manifest radioresistance: Association with upregulated AP-1 activity

Transcription factor AP-1 plays a central role in HPV-mediated cervical carcinogenesis. AP-1 has also been implicated in chemo-radio-resistance but the mechanism(s) remained unexplored. In the present study, cervical cancer stem-like cells (CaCxSLCs) isolated and enriched from cervical cancer cell lines SiHa and C33a demonstrated an elevated AP-1 DNA-binding activity in …

Judgement of the Supreme Court of India regarding approval of Human Papilloma Virus (HPV) vaccine, 05/04/2017

Judgement of the Supreme Court of India in the matter of Kalpana Mehta & Others Vs Union of India & Others dated 05/04/2017 regarding approval of Human Papilloma Virus (HPV) vaccine manufactured by M/s. GlaxoSmithKline Asia Pvt. Ltd. and MSD Pharmaceuticals Private Limited for preventing cervical cancer in women and …

Global trends and predictions in ovarian cancer mortality

Over the last two decades, ovarian cancer mortality rates have levelled or declined. There are, however, persisting and substantial differences in ovarian cancer patterns and trends. Researchers updated global trends in ovarian cancer mortality to 2012, and predicted trends in rates to 2020 using data from the World Health Organization …

Auditing HIV Testing Rates across Europe: Results from the HIDES 2 Study

European guidelines recommend the routine offer of an HIV test in patients with a number of AIDS-defining and non-AIDS conditions believed to share an association with HIV; so called indicator conditions (IC). Adherence with this guidance across Europe is not known. We audited HIV testing behaviour in patients accessing care …

Global surveillance of cancer survival 1995—2009: analysis of individual data for 25 676 887 patients from 279 population-based registries in 67 countries (CONCORD-2)

Worldwide data for cancer survival are scarce. The researchers aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control.

Question raised in Rajya Sabha on high rate of cervical cancer in India, 12/08/2014

Question raised in Rajya Sabha on high rate of cervical cancer in India, 12/08/2014.

Petition filed in the Court of the City of St. Louis State of Missouri regarding linkage between talcum powder and ovarian cancer, 23/06/2014

Petition filed in the Circuit Court of the City of St. Louis State of Missouri in the matter of Angie Wait & Others Vs Johnson & Johnson dated 23/06/2014 regarding linkage between talcum powder and ovarian cancer. All Plaintiffs in this action are seeking "recovery for damages as a result …

Pattern and trends of cancer in Odisha, India: A retrospective study

Epidemic of cancer has transited beyond the geographical boundaries of countries. The globe is under the clutch of this dreadful disease which is spreading rapidly. Nevertheless it is a challenge for any health care system. Every year nearly 10 million people are being diagnosed with cancer out of which about …

Cheaper way for treating cervical cancer: Study

A study by AIIMS has found that the outcomes of a three-step, low-cost, visual screening method for cervical cancer — conducted over a single visit of a patient to the hospital — are similar to the costlier and conventional pap smear method. Doctors have also established that this three-step test, …

Cancer mortality in India: a nationally representative survey

New research analyses cancer death rates across India, and shows that tobacco-related cancers and cervical cancer are important causes of death among working-age people.

Vaccine trial's ethics criticized

A clinical trial that came under fire in India threatens to have a dual legacy: inflaming unfounded fears about a lifesaving vaccine and raising new questions about the management of medical research in the country. http://www.nature.com/news/2011/110622/pdf/474427a.pdf

Body as object: Ethical concerns underlying medical research and practice

What ordinary people would consider violations of ethical norms of society are seldom seen as such by medical practitioners and researchers who may go against such norms in the larger interests of science. The conduct of clinical trials in India illustrates this conflict which arises primarily because of particular objectifications …

Experimenting with the young

The inquiry committee report on the anti-cervical cancer vaccine study project finds serious ethical violations. (Editorial)

The HPV vaccine: Science, ethics and regulation

A recent civil society-led investigation has highlighted serious ethical violations in a trial of the Human Papilloma Virus vaccine on girls in Khammam district in Andhra Pradesh. The findings are presented along with a review of clinical trials of the hpv vaccine in India and an analysis of the Drugs …

Effect of visual screening on cervical cancer incidence and mortality in Tamil Nadu, India: a cluster-randomised trial

Cervical cancer is the most common cancer among women in developing countries. We assessed the effect of screening using visual inspection with 4% acetic acid (VIA) on cervical cancer incidence and mortality in a cluster randomised controlled trial in India.

Effect of visual screening on cervical cancer incidence and mortality in Tamil Nadu, India: a cluster-randomised trial

Cervical cancer is the most common cancer among women in developing countries. We assessed the effect of screening using visual inspection with 4% acetic acid (VIA) on cervical cancer incidence and mortality in a cluster randomised controlled trial in India.

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