Viral Diseases

Order of the National Green Tribunal regarding pollution of Godavari river, Telangana, 29/05/2025

Order of the National Green Tribunal in the matter of News Item titled "Telangana: Deepening pollution crisis in Godawari threatens lives livelihoods appearing in the Telangana Today dated 13.05.2025" dated 29/05/2025. The application was registered suo-motu on the basis of the news item titled Telangana: Deepening pollution crisis in Godawari …

Anticipating the international spread of Zika virus from Brazil

In May, 2015, locally acquired cases of Zika virus—an arbovirus found in Africa and Asia-Pacific and transmitted via Aedes mosquitoes—were confirmed in Brazil. The presence of Aedes mosquitoes across Latin America, coupled with suitable climatic conditions, have triggered a Zika virus epidemic in Brazil, currently estimated at 440 000–1 300 …

Peste des petits ruminants

Peste des petits ruminants virus causes a highly infectious disease of small ruminants that is endemic across Africa, the Middle East and large regions of Asia. The virus is considered to be a major obstacle to the development of sustainable agriculture across the developing world and has recently been targeted …

Judgement of the High Court of Delhi regarding the results of the Multi Centre Clinical Trial of Rotavirus Vaccine done on infants, 14/10/2015

Judgement of the High Court of Delhi in the matter of Jacob Puliyel Vs Union of India & Others dated 14/10/2015. This petition, by way of Public Interest Litigation, is filed seeking a direction to the respondents to provide complete data of the results of the Multi Centre Clinical Trial …

Development of high-yield influenza A virus vaccine viruses

Vaccination is one of the most cost-effective ways to prevent infection. Influenza vaccines propagated in cultured cells are approved for use in humans, but their yields are often suboptimal. Here, we screened A/Puerto Rico/8/34 (PR8) virus mutant libraries to develop vaccine backbones (defined here as the six viral RNA segments …

Saudi Arabia sees Mers deaths surge

Microscope image showing the spherical particles of Mers-CoV within the cytoplasm of an infected cell Image caption This image shows spherical virus particles within the cytoplasm of an infected cell Saudi Arabia has announced four more deaths from Middle East Respiratory Syndrome (Mers), bringing the number of deaths in the …

E3 ubiquitin ligase NEDD4 promotes influenza virus infection by decreasing levels of the antiviral protein IFITM3

IFITM3 is critical for limiting the severity of influenza virus infections in humans and mice. Optimal antiviral activity of IFITM3 is achieved when it is present at high levels within cells. Our results indicate that the E3 ubiquitin ligase NEDD4 decreases baseline IFITM3 levels by ubiquitinating IFITM3 and promoting its …

Mers outbreak in the UK: Manchester Royal Infirmary A&E shuts down after two suspected cases

An Accident and Emergency department in Manchester has been shut down following two suspected cases of Mers-CoV (Middle Eastern Respiratory Syndrome coronavirus). The NHS confirmed the A&E; department at the Manchester Royal Infirmary has been closed in a statement, saying medical officers are currently examining two patients suspected of having …

South Korea sees end of MERS threat after outbreak killed 36

South Korea said Tuesday it is now virtually free of the deadly MERS virus that killed 36 people and sickened nearly 200 since an outbreak was declared in May. Prime Minister Hwang Kyo-ahn in a government meeting urged people to return to normal as the country hasn't had a new …

Hepatitis causes over 1.4m deaths yearly, 80% of liver cancer, says WHO

AS part of activities to mark the World Hepatitis Day (WHD), today, July 28, 2015, the World Health Organisation (WHO) has highlighted the urgent need for countries to enhance action to prevent viral hepatitis infection and to ensure that people who have been infected are diagnosed and offered treatment. The …

Philippines confirms second MERS case

The Philippines confirmed a second case of the deadly Middle East Respiratory Syndrome (MERS) corona virus on Monday in a man who showed symptoms after arriving in Manila last month from Dubai. The 36-year-old was admitted to hospital on Saturday and was under observation, Health Ministry spokesman Lyndon Lee-suy said, …

1 more MERS infection added in S. Korea, first in 5 days

One more case of infection with Middle East Respiratory Syndrome (MERS) was added in South Korea Thursday, marking the first case in five days, the health ministry said. The patient 183 was a nurse at the Samsung Medical Center in Seoul, where 88 people, or 48 percent of the total, …

Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection

Traditional approaches for development of antibodies are poorly suited to combating the emergence of novel pathogens, as they require multiple steps of laborious optimization and process adaptation for clinical development. Here, we describe the simultaneous use of two state-of-the-art technologies to rapidly generate and validate antibodies against Middle East Respiratory …

S. Korea cautiously reports no new MERS cases or deaths

South Korea reported no new cases of MERS or deaths from the virus for the first time in nine days Monday, but officials warned there was no indication yet that the outbreak had been brought under control. The number of those infected with Middle East Respiratory Syndrome remained unchanged for …

Avian influenza virus exhibits distinct evolutionary dynamics in wild birds and poultry

Wild birds are the major reservoir hosts for influenza A viruses, occasionally transmitting to other species such as domesticated poultry. Despite an abundance of genomic data from avian influenza virus (AIV), little is known about whether AIV evolves differently in wild birds and poultry, although this is critical to revealing …

South Korea reports two more deaths in MERS outbreak bringing total to 29

South Korea's Health Ministry reported on Thursday two more deaths in a Middle East Respiratory Syndrome (MERS) outbreak, bringing the number of fatalities to 29. The ministry also said there was one new case confirmed taking the total to 180 in the outbreak that is the largest outside Saudi Arabia, …

Effect of the Ebola-virus-disease epidemic on malaria case management in Guinea, 2014: a cross-sectional survey of health facilities

The ongoing west Africa Ebola-virus-disease epidemic has disrupted the entire health-care system in affected countries. Because of the overlap of symptoms of Ebola virus disease and malaria, the care delivery of malaria is particularly sensitive to the indirect effects of the current Ebola-virus-disease epidemic. We therefore characterise malaria case management …

S Korea reports 3 more MERS infections, 2 deaths

SOUTH Korean reported three more cases of infection with the Middle East Respiratory Syndrome (MERS) and two deaths today, bringing the total contagion cases to 172 and the death toll to 27. Among the three new cases was the 171st patient, who tested positive 10 days after the incubation period …

S Korea reports 3 more MERS infections, 2 deaths

SOUTH Korean reported three more cases of infection with the Middle East Respiratory Syndrome (MERS) and two deaths today, bringing the total contagion cases to 172 and the death toll to 27. Among the three new cases was the 171st patient, who tested positive 10 days after the incubation period …

South Korea MERS outbreak has 'levelled off'; one new case

An outbreak of Middle East Respiratory Syndrome (MERS) in South Korea appears to have levelled off, a health official said on Friday, as the country reported just one new patient, a day after Thailand reported its first case. A total of 166 people have been infected in the South Korean …

Successes and challenges on the road to cure Hepatitis C

Hepatitis C virus (HCV) represents a significant health burden worldwide, with an estimated 185 million people chronically infected. A leading cause of liver transplantation, HCV infection can result in severe liver disease including cirrhosis and hepatocellular carcinoma. Cure of HCV infection results in substantial decreases in such liver-related morbidity and …

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