Micro Organisms

State of the Climate in Asia 2024

The World Meteorological Organization’s State of the Climate in Asia 2024 report warns that the region is warming nearly twice as fast as the global average, driving more extreme weather and posing serious threats to lives, ecosystems, and economies. In 2024, Asia experienced its warmest or second warmest year on …

Isolation and characterization of three and four ring PAHs degrading bacteria from contaminated sites, Ankleshwar, Gujarat, India

Polycyclic aromatic hydrocarbon (PAH)-degrading bacteria were isolated from prolong contaminated Amalakhadi sediment and crude oil polluted soil Telva, near Ankleshwar Gujarat India. Organisms were treated with two-model PAHs compound Anthracene (ANT), and Pyrene (PYR) as the sole source of carbon and energy. Identification of the isolates was carried out based …

Coping with climate change: the roles of genetic resources for food and agriculture

Genetic resources for food and agriculture play a crucial role in food security, nutrition and livelihoods and in the provision of environmental services. They are key components of sustainability, resilience and adaptability in production systems. They underpin the ability of crops, livestock, aquatic organisms and forest trees to withstand a …

New Species Discovered Two Miles Below the Surface of the Ocean

Two miles below the surface of the ocean, a strange species of microbes thrives. Now, scientists have learned a bit more about these new microbes that "breathe" sulfate. The microbes have yet to be classified and named, but they exist in massive undersea aquifers, which are networks of channels in …

A new antibiotic kills pathogens without detectable resistance

Antibiotic resistance is spreading faster than the introduction of new compounds into clinical practice, causing a public health crisis. Most antibiotics were produced by screening soil microorganisms, but this limited resource of cultivable bacteria was overmined by the 1960s. Synthetic approaches to produce antibiotics have been unable to replace this …

Antibiotic resistance in prevalent bacterial and protozoan sexually transmitted infections

The emergence of multi-drug resistant sexually transmitted infections (STIs) is causing a treatment crisis across the globe. While cephalosporin-resistant gonorrhea is one of the most pressing issues, extensively antibiotic resistant Chlamydia trachomatis and Mycoplasma hominis are also becoming commonplace. Experts have suggested that the failure of current treatment regimens are …

Seasonal variation of soil enzymes in fluoride stress area of Birbhum district, West Bengal, India

Soil enzyme activities provide unique biochemical assessment of soil function as a good indicator of soil fertility which can be altered due to the profusion of fluoride in soil and seasonal change. Seven sites were chosen in the fluoride affected area of Nasipur, Birbhum district, West Bengal, India, to make …

Chemical and microbial characterization of surface and ground waters near estuaries of East Godavari region for evaluation of their potential for application

Surface and ground water are systems linked with each other. In coastal region salanization problem is significant for groundwater contamination. The transition of ground water in to the surface waters contributes a noticeable change in teh ground water environment besides heavy metal cycling. Due to natural and anthropogenic activities the …

Exploring gut microbes in human health and disease: Pushing the envelope

Humans have coevolved with their microbes over thousands of years, but this relationship, is now being dramatically affected by shifts in the collective human microbiome resulting from changes in the environment and societal norms. Resulting perturbations of intestinal host-microbe interactions can lead to miscues and altered host responses that increase …

Weaker soil carbon–climate feedbacks resulting from microbial and abiotic interactions

The large uncertainty in soil carbon–climate feedback predictions has been attributed to the incorrect parameterization of decomposition temperature sensitivity and microbial carbon use efficiency. Empirical experiments have found that these parameters vary spatiotemporally, but such variability is not included in current ecosystem models. Here we use a thermodynamically based decomposition …

The path of least resistance: aggressive or moderate treatment?

The evolution of resistance to antimicrobial chemotherapy is a major and growing cause of human mortality and morbidity. Comparatively little attention has been paid to how different patient treatment strategies shape the evolution of resistance. In particular, it is not clear whether treating individual patients aggressively with high drug dosages …

Microbial assessment and prevalence of antibiotic resistance in polluted Oluwa River, Nigeria

Antibiotics are emerging environmental contaminants, causing both short-term and long-term alterations of natural microbial communities due to their high biological activities. The antibiotic resistance pattern of bacteria from anthropogenic polluted Oluwa River, Nigeria was carried out. Microbial profiling and antibiotic sensitivity tests were carried out on water and sediment samples …

‘Division of labour’ in response to host oxidative burst drives a fatal Cryptococcus gattii outbreak

Cryptococcus gattii is an emerging intracellular pathogen and the cause of the largest primary outbreak of a life-threatening fungal disease in a healthy population. Outbreak strains share a unique mitochondrial gene expression profile and an increased ability to tubularize their mitochondria within host macrophages. However, the underlying mechanism that causes …

House fly genome could help protect environment

The house fly could be a carrier of over 100 human diseases, but its genome may help humans deal with toxic and disease causing environments, found a research. Genome is the complete set of genes present in a cell or organism. The 691 Mb genome that has been sequenced and …

Dissemination of antibiotic resistance genes in representative broiler feedlots environments: Identification of indicator ARGs and correlations with environmental variables

Livestock operations are known to harbor elevated levels of antibiotic resistance genes (ARGs) that may pose a threat to public health. Broiler feedlots may represent an important source of ARGs in the environment. However, the prevalence and dissemination mechanisms of various types of ARGs in the environment of broiler feedlots …

Biogeography of human infectious diseases: A global historical analysis

Human pathogen richness and prevalence vary widely across the globe, yet we know little about whether global patterns found in other taxa also predict diversity in this important group of organisms. This study (a) assesses the relative importance of temperature, precipitation, habitat diversity, and population density on the global distributions …

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations

Repeated exposure of the bacterium Escherichia coli to clinically relevant concentrations of ampicillin results in the evolution of tolerance—the ability to survive until the antibiotic concentration diminishes—through an extension of the lag phase, a finding that has implications for slowing the evolution of antibiotic resistance.

Discovery of a small molecule that inhibits bacterial ribosome biogenesis

While small molecule inhibitors of the bacterial ribosome have been instrumental in understanding protein translation, no such probes exist to study ribosome biogenesis. We screened a diverse chemical collection that included previously approved drugs for compounds that induced cold sensitive growth inhibition in the model bacterium Escherichia coli. Among the …

The human body can be mined for antibiotics, shows latest research

“Microorganisms are the best chemists on the planet,” declared Michael A. Fischbach, a chemist at the University of California, San Francisco. For evidence, Fischbach points to the many lifesaving drugs that microorganisms produce. In 1928, for example, Alexander Fleming discovered that mould wafting into his lab produced a bacteria-killing chemical …

Metagenomic analysis of double-stranded DNA viruses in healthy adults

The Human Microbiome Project (HMP) was undertaken with the goal of defining microbial communities in and on the bodies of healthy individuals using high-throughput, metagenomic sequencing analysis. The viruses present in these microbial communities, the `human virome?, are an important aspect of the human microbiome that is particularly understudied in …

Temperature sensitivity of soil respiration rates enhanced by microbial community response

oils store about four times as much carbon as plant biomass, and soil microbial respiration releases about 60 petagrams of carbon per year to the atmosphere as carbon dioxide. Short-term experiments have shown that soil microbial respiration increases exponentially with temperature. This information has been incorporated into soil carbon and …

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